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Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya.
Ogutu BR, Apollo OJ, McKinney D, Okoth W, Siangla J, Dubovsky F, Tucker K, Waitumbi JN, Diggs C, Wittes J, Malkin E, Leach A, Soisson LA, Milman JB, Otieno L, Holland CA, Polhemus M, Remich SA, Ockenhouse CF, Cohen J, Ballou WR, Martin SK, Angov E, Stewart VA, Lyon JA, Heppner DG, Withers MR; MSP-1 Malaria Vaccine Working Group. Ogutu BR, et al. Among authors: heppner dg. PLoS One. 2009;4(3):e4708. doi: 10.1371/journal.pone.0004708. Epub 2009 Mar 5. PLoS One. 2009. PMID: 19262754 Free PMC article. Clinical Trial.
Field trials of an asexual blood stage malaria vaccine: studies of the synthetic peptide polymer SPf66 in Thailand and the analytic plan for a phase IIb efficacy study.
Ballou WR, Blood J, Chongsuphajaissidhi T, Gordon DM, Heppner DG, Kyle DE, Luxemburger C, Nosten F, Sadoff JC, Singhasivanon P, et al. Ballou WR, et al. Among authors: heppner dg. Parasitology. 1995;110 Suppl:S25-36. doi: 10.1017/s0031182000001463. Parasitology. 1995. PMID: 7784126 Clinical Trial.
Phase I safety and immunogenicity testing of clinical lots of the synthetic Plasmodium falciparum vaccine SPf66 produced under good manufacturing procedure conditions in the United States.
Gordon DM, Duffy PE, Heppner DG, Lyon JA, Williams JS, Scheumann D, Farley L, Stacey D, Haynes JD, Sadoff JC, Ballou WR. Gordon DM, et al. Among authors: heppner dg. Am J Trop Med Hyg. 1996 Jul;55(1):63-8. doi: 10.4269/ajtmh.1996.55.63. Am J Trop Med Hyg. 1996. PMID: 8702024 Clinical Trial.
SPf66 malaria vaccine is safe and immunogenic in malaria naive adults in Thailand.
Migasena S, Heppner DG, Kyle DE, Chongsuphajaisiddhi T, Gordon DM, Suntharasamai P, Permpanich B, Brockman A, Pitiuttutham P, Wongsrichanalai C, Srisuriya P, Phonrat B, Pavanand K, Viravan C, Ballou WR. Migasena S, et al. Among authors: heppner dg. Acta Trop. 1997 Sep 30;67(3):215-27. doi: 10.1016/s0001-706x(97)00061-2. Acta Trop. 1997. PMID: 9241386 Clinical Trial.
120 results