Frazier WA - Search Results

1

CD47 regulates bone mass and tumor metastasis to bone.

Uluçkan O, Becker SN, Deng H, Zou W, Prior JL, Piwnica-Worms D, Frazier WA, Weilbaecher KN. Uluçkan O, et al. Among authors: frazier wa. Cancer Res. 2009 Apr 1;69(7):3196-204. doi: 10.1158/0008-5472.CAN-08-3358. Epub 2009 Mar 10. Cancer Res. 2009. PMID: 19276363 Free PMC article.

2

Thrombospondin-1 regulates bone homeostasis through effects on bone matrix integrity and nitric oxide signaling in osteoclasts.

Amend SR, Uluckan O, Hurchla M, Leib D, Novack DV, Silva M, Frazier W, Weilbaecher KN. Amend SR, et al. J Bone Miner Res. 2015 Jan;30(1):106-15. doi: 10.1002/jbmr.2308. J Bone Miner Res. 2015. PMID: 25042340 Free PMC article.

3

CD47 mediates killing of breast tumor cells via Gi-dependent inhibition of protein kinase A.

Manna PP, Frazier WA. Manna PP, et al. Among authors: frazier wa. Cancer Res. 2004 Feb 1;64(3):1026-36. doi: 10.1158/0008-5472.can-03-1708. Cancer Res. 2004. PMID: 14871834

4

Antibody mediated therapy targeting CD47 inhibits tumor progression of hepatocellular carcinoma.

Xiao Z, Chung H, Banan B, Manning PT, Ott KC, Lin S, Capoccia BJ, Subramanian V, Hiebsch RR, Upadhya GA, Mohanakumar T, Frazier WA, Lin Y, Chapman WC. Xiao Z, et al. Among authors: frazier wa. Cancer Lett. 2015 May 1;360(2):302-9. doi: 10.1016/j.canlet.2015.02.036. Epub 2015 Feb 23. Cancer Lett. 2015. PMID: 25721088 Free PMC article.

5

Development of AO-176, a Next-Generation Humanized Anti-CD47 Antibody with Novel Anticancer Properties and Negligible Red Blood Cell Binding.

Puro RJ, Bouchlaka MN, Hiebsch RR, Capoccia BJ, Donio MJ, Manning PT, Frazier WA, Karr RW, Pereira DS. Puro RJ, et al. Among authors: frazier wa. Mol Cancer Ther. 2020 Mar;19(3):835-846. doi: 10.1158/1535-7163.MCT-19-1079. Epub 2019 Dec 26. Mol Cancer Ther. 2020. PMID: 31879362

6

CD47 augments Fas/CD95-mediated apoptosis.

Manna PP, Dimitry J, Oldenborg PA, Frazier WA. Manna PP, et al. Among authors: frazier wa. J Biol Chem. 2005 Aug 19;280(33):29637-44. doi: 10.1074/jbc.M500922200. Epub 2005 May 24. J Biol Chem. 2005. PMID: 15917238 Free article.

7

CD47 plays a critical role in T-cell recruitment by regulation of LFA-1 and VLA-4 integrin adhesive functions.

Azcutia V, Routledge M, Williams MR, Newton G, Frazier WA, Manica A, Croce KJ, Parkos CA, Schmider AB, Turman MV, Soberman RJ, Luscinskas FW. Azcutia V, et al. Among authors: frazier wa. Mol Biol Cell. 2013 Nov;24(21):3358-68. doi: 10.1091/mbc.E13-01-0063. Epub 2013 Sep 4. Mol Biol Cell. 2013. PMID: 24006483 Free PMC article.

8

CD47 blockade reduces ischemia-reperfusion injury and improves outcomes in a rat kidney transplant model.

Lin Y, Manning PT, Jia J, Gaut JP, Xiao Z, Capoccia BJ, Chen CC, Hiebsch RR, Upadhya G, Mohanakumar T, Frazier WA, Chapman WC. Lin Y, et al. Among authors: frazier wa. Transplantation. 2014 Aug 27;98(4):394-401. doi: 10.1097/TP.0000000000000252. Transplantation. 2014. PMID: 24983310 Free PMC article.

9

The thrombospondin receptor CD47 (IAP) modulates and associates with alpha2 beta1 integrin in vascular smooth muscle cells.

Wang XQ, Frazier WA. Wang XQ, et al. Among authors: frazier wa. Mol Biol Cell. 1998 Apr;9(4):865-74. doi: 10.1091/mbc.9.4.865. Mol Biol Cell. 1998. PMID: 9529384 Free PMC article.

10

Age-dependent regulation of skeletal muscle mitochondria by the thrombospondin-1 receptor CD47.

Frazier EP, Isenberg JS, Shiva S, Zhao L, Schlesinger P, Dimitry J, Abu-Asab MS, Tsokos M, Roberts DD, Frazier WA. Frazier EP, et al. Among authors: frazier wa. Matrix Biol. 2011 Mar;30(2):154-61. doi: 10.1016/j.matbio.2010.12.004. Epub 2011 Jan 20. Matrix Biol. 2011. PMID: 21256215 Free PMC article.

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