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In vitro and in vivo SAR of pyrido[3,4-d]pyramid-4-ylamine based mGluR1 antagonists.
Bioorg Med Chem Lett. 2009 Apr 15;19(8):2190-4. doi: 10.1016/j.bmcl.2009.02.106. Epub 2009 Mar 3.
Bioorg Med Chem Lett. 2009.
PMID: 19289283
Design, synthesis and biological activity of beta-carboline-based type-5 phosphodiesterase inhibitors.
Maw GN, Allerton CM, Gbekor E, Million WA.
Maw GN, et al. Among authors: million wa.
Bioorg Med Chem Lett. 2003 Apr 17;13(8):1425-8. doi: 10.1016/s0960-894x(03)00159-8.
Bioorg Med Chem Lett. 2003.
PMID: 12668004
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Highly potent and selective zwitterionic agonists of the delta-opioid receptor. Part 1.
Middleton DS, Maw GN, Challenger C, Jessiman A, Johnson PS, Million WA, Nichols CL, Price JA, Trevethick M.
Middleton DS, et al. Among authors: million wa.
Bioorg Med Chem Lett. 2006 Feb 15;16(4):905-10. doi: 10.1016/j.bmcl.2005.10.102. Epub 2005 Nov 15.
Bioorg Med Chem Lett. 2006.
PMID: 16290934
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The discovery of UK-369003, a novel PDE5 inhibitor with the potential for oral bioavailability and dose-proportional pharmacokinetics.
Rawson DJ, Ballard S, Barber C, Barker L, Beaumont K, Bunnage M, Cole S, Corless M, Denton S, Ellis D, Floc'h M, Foster L, Gosset J, Holmwood F, Lane C, Leahy D, Mathias J, Maw G, Million W, Poinsard C, Price J, Russel R, Street S, Watson L.
Rawson DJ, et al.
Bioorg Med Chem. 2012 Jan 1;20(1):498-509. doi: 10.1016/j.bmc.2011.10.022. Epub 2011 Oct 24.
Bioorg Med Chem. 2012.
PMID: 22100260
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Discovery and Optimization of Selective Nav1.8 Modulator Series That Demonstrate Efficacy in Preclinical Models of Pain.
Bagal SK, Bungay PJ, Denton SM, Gibson KR, Glossop MS, Hay TL, Kemp MI, Lane CA, Lewis ML, Maw GN, Million WA, Payne CE, Poinsard C, Rawson DJ, Stammen BL, Stevens EB, Thompson LR.
Bagal SK, et al. Among authors: million wa.
ACS Med Chem Lett. 2015 Apr 29;6(6):650-4. doi: 10.1021/acsmedchemlett.5b00059. eCollection 2015 Jun 11.
ACS Med Chem Lett. 2015.
PMID: 26101568
Free PMC article.
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