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CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance.
Chavey C, Lazennec G, Lagarrigue S, Clapé C, Iankova I, Teyssier J, Annicotte JS, Schmidt J, Mataki C, Yamamoto H, Sanches R, Guma A, Stich V, Vitkova M, Jardin-Watelet B, Renard E, Strieter R, Tuthill A, Hotamisligil GS, Vidal-Puig A, Zorzano A, Langin D, Fajas L. Chavey C, et al. Among authors: lagarrigue s. Cell Metab. 2009 Apr;9(4):339-49. doi: 10.1016/j.cmet.2009.03.002. Cell Metab. 2009. PMID: 19356715 Free PMC article.
[Emerging key role of cell cycle regulators in cell metabolism].
Lagarrigue S, Blanchet É, Annicotte JS, Fajas L. Lagarrigue S, et al. Med Sci (Paris). 2011 May;27(5):508-13. doi: 10.1051/medsci/2011275016. Epub 2011 May 25. Med Sci (Paris). 2011. PMID: 21609672 Free article. Review. French.
E2F transcription factor-1 regulates oxidative metabolism.
Blanchet E, Annicotte JS, Lagarrigue S, Aguilar V, Clapé C, Chavey C, Fritz V, Casas F, Apparailly F, Auwerx J, Fajas L. Blanchet E, et al. Among authors: lagarrigue s. Nat Cell Biol. 2011 Aug 14;13(9):1146-52. doi: 10.1038/ncb2309. Nat Cell Biol. 2011. PMID: 21841792 Free PMC article.
CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L. Lagarrigue S, et al. J Clin Invest. 2016 Jan;126(1):335-48. doi: 10.1172/JCI81480. Epub 2015 Dec 14. J Clin Invest. 2016. PMID: 26657864 Free PMC article.
CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation.
Lopez-Mejia IC, Lagarrigue S, Giralt A, Martinez-Carreres L, Zanou N, Denechaud PD, Castillo-Armengol J, Chavey C, Orpinell M, Delacuisine B, Nasrallah A, Collodet C, Zhang L, Viollet B, Hardie DG, Fajas L. Lopez-Mejia IC, et al. Among authors: lagarrigue s. Mol Cell. 2017 Oct 19;68(2):336-349.e6. doi: 10.1016/j.molcel.2017.09.034. Mol Cell. 2017. PMID: 29053957 Free article.
CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L. Lagarrigue S, et al. J Clin Invest. 2022 Jul 1;132(13):e162359. doi: 10.1172/JCI162359. J Clin Invest. 2022. PMID: 35775487 Free PMC article. No abstract available.
Hypothalamic CDK4 regulates thermogenesis by modulating sympathetic innervation of adipose tissues.
Castillo-Armengol J, Barquissau V, Geller S, Ji H, Severi I, Venema W, Fenandez EA, Moret C, Huber K, Leal-Esteban LC, Nasrallah A, Martinez-Carreres L, Niederhäuser G, Seoane-Collazo P, Lagarrigue S, López M, Giordano A, Croizier S, Thorens B, Lopez-Mejia IC, Fajas L. Castillo-Armengol J, et al. Among authors: lagarrigue s. EMBO Rep. 2020 Sep 3;21(9):e49807. doi: 10.15252/embr.201949807. Epub 2020 Jul 12. EMBO Rep. 2020. PMID: 32657019 Free PMC article.
98 results