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CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance.
Chavey C, Lazennec G, Lagarrigue S, Clapé C, Iankova I, Teyssier J, Annicotte JS, Schmidt J, Mataki C, Yamamoto H, Sanches R, Guma A, Stich V, Vitkova M, Jardin-Watelet B, Renard E, Strieter R, Tuthill A, Hotamisligil GS, Vidal-Puig A, Zorzano A, Langin D, Fajas L. Chavey C, et al. Among authors: yamamoto h. Cell Metab. 2009 Apr;9(4):339-49. doi: 10.1016/j.cmet.2009.03.002. Cell Metab. 2009. PMID: 19356715 Free PMC article.
TGR5-mediated bile acid sensing controls glucose homeostasis.
Thomas C, Gioiello A, Noriega L, Strehle A, Oury J, Rizzo G, Macchiarulo A, Yamamoto H, Mataki C, Pruzanski M, Pellicciari R, Auwerx J, Schoonjans K. Thomas C, et al. Among authors: yamamoto h. Cell Metab. 2009 Sep;10(3):167-77. doi: 10.1016/j.cmet.2009.08.001. Cell Metab. 2009. PMID: 19723493 Free PMC article.
PARP-2 regulates SIRT1 expression and whole-body energy expenditure.
Bai P, Canto C, Brunyánszki A, Huber A, Szántó M, Cen Y, Yamamoto H, Houten SM, Kiss B, Oudart H, Gergely P, Menissier-de Murcia J, Schreiber V, Sauve AA, Auwerx J. Bai P, et al. Among authors: yamamoto h. Cell Metab. 2011 Apr 6;13(4):450-460. doi: 10.1016/j.cmet.2011.03.013. Cell Metab. 2011. PMID: 21459329 Free PMC article.
LRH-1-dependent glucose sensing determines intermediary metabolism in liver.
Oosterveer MH, Mataki C, Yamamoto H, Harach T, Moullan N, van Dijk TH, Ayuso E, Bosch F, Postic C, Groen AK, Auwerx J, Schoonjans K. Oosterveer MH, et al. Among authors: yamamoto h. J Clin Invest. 2012 Aug;122(8):2817-26. doi: 10.1172/JCI62368. Epub 2012 Jul 9. J Clin Invest. 2012. PMID: 22772466 Free PMC article.
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation.
Bai P, Cantó C, Oudart H, Brunyánszki A, Cen Y, Thomas C, Yamamoto H, Huber A, Kiss B, Houtkooper RH, Schoonjans K, Schreiber V, Sauve AA, Menissier-de Murcia J, Auwerx J. Bai P, et al. Among authors: yamamoto h. Cell Metab. 2011 Apr 6;13(4):461-468. doi: 10.1016/j.cmet.2011.03.004. Cell Metab. 2011. PMID: 21459330 Free PMC article.
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.
Cantó C, Houtkooper RH, Pirinen E, Youn DY, Oosterveer MH, Cen Y, Fernandez-Marcos PJ, Yamamoto H, Andreux PA, Cettour-Rose P, Gademann K, Rinsch C, Schoonjans K, Sauve AA, Auwerx J. Cantó C, et al. Among authors: yamamoto h. Cell Metab. 2012 Jun 6;15(6):838-47. doi: 10.1016/j.cmet.2012.04.022. Cell Metab. 2012. PMID: 22682224 Free PMC article.
SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity.
Rutanen J, Yaluri N, Modi S, Pihlajamäki J, Vänttinen M, Itkonen P, Kainulainen S, Yamamoto H, Lagouge M, Sinclair DA, Elliott P, Westphal C, Auwerx J, Laakso M. Rutanen J, et al. Among authors: yamamoto h. Diabetes. 2010 Apr;59(4):829-35. doi: 10.2337/db09-1191. Epub 2010 Jan 27. Diabetes. 2010. PMID: 20107110 Free PMC article.
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