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Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance.
Grünberg JR, Hoffmann JM, Hedjazifar S, Nerstedt A, Jenndahl L, Elvin J, Castellot J, Wei L, Movérare-Skrtic S, Ohlsson C, Holm LM, Bäckhed F, Syed I, Bosch F, Saghatelian A, Kahn BB, Hammarstedt A, Smith U. Grünberg JR, et al. Among authors: backhed f. Sci Rep. 2017 Feb 27;7:43515. doi: 10.1038/srep43515. Sci Rep. 2017. PMID: 28240264 Free PMC article.
Enterotypes in the landscape of gut microbial community composition.
Costea PI, Hildebrand F, Arumugam M, Bäckhed F, Blaser MJ, Bushman FD, de Vos WM, Ehrlich SD, Fraser CM, Hattori M, Huttenhower C, Jeffery IB, Knights D, Lewis JD, Ley RE, Ochman H, O'Toole PW, Quince C, Relman DA, Shanahan F, Sunagawa S, Wang J, Weinstock GM, Wu GD, Zeller G, Zhao L, Raes J, Knight R, Bork P. Costea PI, et al. Among authors: backhed f. Nat Microbiol. 2018 Jan;3(1):8-16. doi: 10.1038/s41564-017-0072-8. Epub 2017 Dec 18. Nat Microbiol. 2018. PMID: 29255284 Free PMC article. Review.
Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41.
Samuel BS, Shaito A, Motoike T, Rey FE, Backhed F, Manchester JK, Hammer RE, Williams SC, Crowley J, Yanagisawa M, Gordon JI. Samuel BS, et al. Among authors: backhed f. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16767-72. doi: 10.1073/pnas.0808567105. Epub 2008 Oct 17. Proc Natl Acad Sci U S A. 2008. PMID: 18931303 Free PMC article.
Combinatorial, additive and dose-dependent drug-microbiome associations.
Forslund SK, Chakaroun R, Zimmermann-Kogadeeva M, Markó L, Aron-Wisnewsky J, Nielsen T, Moitinho-Silva L, Schmidt TSB, Falony G, Vieira-Silva S, Adriouch S, Alves RJ, Assmann K, Bastard JP, Birkner T, Caesar R, Chilloux J, Coelho LP, Fezeu L, Galleron N, Helft G, Isnard R, Ji B, Kuhn M, Le Chatelier E, Myridakis A, Olsson L, Pons N, Prifti E, Quinquis B, Roume H, Salem JE, Sokolovska N, Tremaroli V, Valles-Colomer M, Lewinter C, Søndertoft NB, Pedersen HK, Hansen TH; MetaCardis Consortium*; Gøtze JP, Køber L, Vestergaard H, Hansen T, Zucker JD, Hercberg S, Oppert JM, Letunic I, Nielsen J, Bäckhed F, Ehrlich SD, Dumas ME, Raes J, Pedersen O, Clément K, Stumvoll M, Bork P. Forslund SK, et al. Among authors: backhed f. Nature. 2021 Dec;600(7889):500-505. doi: 10.1038/s41586-021-04177-9. Epub 2021 Dec 8. Nature. 2021. PMID: 34880489
A systems biology approach to study non-alcoholic fatty liver (NAFL) in women with obesity.
Meijnikman AS, Lappa D, Herrema H, Aydin O, Krautkramer KA, Tremaroli V, Olofsson LE, Lundqvist A, Bruin S, Acherman Y, Verheij J, Hjorth S, Gerdes VEA, Schwartz TW, Groen AK, Bäckhed F, Nielsen J, Nieuwdorp M. Meijnikman AS, et al. Among authors: backhed f. iScience. 2022 Aug 5;25(8):104828. doi: 10.1016/j.isci.2022.104828. eCollection 2022 Aug 19. iScience. 2022. PMID: 35992074 Free PMC article.
Feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mTORC1 signaling in obese mice.
Choi BS, Daniel N, Houde VP, Ouellette A, Marcotte B, Varin TV, Vors C, Feutry P, Ilkayeva O, Ståhlman M, St-Pierre P, Bäckhed F, Tremblay A, White PJ, Marette A. Choi BS, et al. Among authors: backhed f. Nat Commun. 2021 Jun 7;12(1):3377. doi: 10.1038/s41467-021-23782-w. Nat Commun. 2021. PMID: 34099716 Free PMC article.
Depicting the composition of gut microbiota in a population with varied ethnic origins but shared geography.
Deschasaux M, Bouter KE, Prodan A, Levin E, Groen AK, Herrema H, Tremaroli V, Bakker GJ, Attaye I, Pinto-Sietsma SJ, van Raalte DH, Snijder MB, Nicolaou M, Peters R, Zwinderman AH, Bäckhed F, Nieuwdorp M. Deschasaux M, et al. Among authors: backhed f. Nat Med. 2018 Oct;24(10):1526-1531. doi: 10.1038/s41591-018-0160-1. Epub 2018 Aug 27. Nat Med. 2018. PMID: 30150717
244 results