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Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13.
Burkhardt R, Kenny EE, Lowe JK, Birkeland A, Josowitz R, Noel M, Salit J, Maller JB, Pe'er I, Daly MJ, Altshuler D, Stoffel M, Friedman JM, Breslow JL. Burkhardt R, et al. Among authors: friedman jm. Arterioscler Thromb Vasc Biol. 2008 Nov;28(11):2078-84. doi: 10.1161/ATVBAHA.108.172288. Epub 2008 Sep 18. Arterioscler Thromb Vasc Biol. 2008. PMID: 18802019 Free PMC article.
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
Lowe JK, Maller JB, Pe'er I, Neale BM, Salit J, Kenny EE, Shea JL, Burkhardt R, Smith JG, Ji W, Noel M, Foo JN, Blundell ML, Skilling V, Garcia L, Sullivan ML, Lee HE, Labek A, Ferdowsian H, Auerbach SB, Lifton RP, Newton-Cheh C, Breslow JL, Stoffel M, Daly MJ, Altshuler DM, Friedman JM. Lowe JK, et al. Among authors: friedman jm. PLoS Genet. 2009 Feb;5(2):e1000365. doi: 10.1371/journal.pgen.1000365. Epub 2009 Feb 6. PLoS Genet. 2009. PMID: 19197348 Free PMC article.
Systematic haplotype analysis resolves a complex plasma plant sterol locus on the Micronesian Island of Kosrae.
Kenny EE, Gusev A, Riegel K, Lütjohann D, Lowe JK, Salit J, Maller JB, Stoffel M, Daly MJ, Altshuler DM, Friedman JM, Breslow JL, Pe'er I, Sehayek E. Kenny EE, et al. Among authors: friedman jm. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13886-91. doi: 10.1073/pnas.0907336106. Epub 2009 Aug 10. Proc Natl Acad Sci U S A. 2009. PMID: 19667188 Free PMC article.
Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population.
Kenny EE, Kim M, Gusev A, Lowe JK, Salit J, Smith JG, Kovvali S, Kang HM, Newton-Cheh C, Daly MJ, Stoffel M, Altshuler DM, Friedman JM, Eskin E, Breslow JL, Pe'er I. Kenny EE, et al. Among authors: friedman jm. Hum Mol Genet. 2011 Feb 15;20(4):827-39. doi: 10.1093/hmg/ddq510. Epub 2010 Nov 30. Hum Mol Genet. 2011. PMID: 21118897 Free PMC article.
Whole population, genome-wide mapping of hidden relatedness.
Gusev A, Lowe JK, Stoffel M, Daly MJ, Altshuler D, Breslow JL, Friedman JM, Pe'er I. Gusev A, et al. Among authors: friedman jm. Genome Res. 2009 Feb;19(2):318-26. doi: 10.1101/gr.081398.108. Epub 2008 Oct 29. Genome Res. 2009. PMID: 18971310 Free PMC article.
829 results