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Follicle-stimulating hormone increases cholangiocyte proliferation by an autocrine mechanism via cAMP-dependent phosphorylation of ERK1/2 and Elk-1.
Mancinelli R, Onori P, Gaudio E, DeMorrow S, Franchitto A, Francis H, Glaser S, Carpino G, Venter J, Alvaro D, Kopriva S, White M, Kossie A, Savage J, Alpini G. Mancinelli R, et al. Among authors: alvaro d. Am J Physiol Gastrointest Liver Physiol. 2009 Jul;297(1):G11-26. doi: 10.1152/ajpgi.00025.2009. Epub 2009 Apr 23. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19389804 Free PMC article.
Taurocholate feeding prevents CCl4-induced damage of large cholangiocytes through PI3-kinase-dependent mechanism.
Marucci L, Alpini G, Glaser SS, Alvaro D, Benedetti A, Francis H, Phinizy JL, Marzioni M, Mauldin J, Venter J, Baumann B, Ugili L, LeSage G. Marucci L, et al. Among authors: alvaro d. Am J Physiol Gastrointest Liver Physiol. 2003 Feb;284(2):G290-301. doi: 10.1152/ajpgi.00245.2002. Epub 2002 Oct 2. Am J Physiol Gastrointest Liver Physiol. 2003. PMID: 12388182 Free article.
Adrenergic receptor agonists prevent bile duct injury induced by adrenergic denervation by increased cAMP levels and activation of Akt.
Glaser S, Alvaro D, Francis H, Ueno Y, Marucci L, Benedetti A, De Morrow S, Marzioni M, Mancino MG, Phinizy JL, Reichenbach R, Fava G, Summers R, Venter J, Alpini G. Glaser S, et al. Among authors: alvaro d. Am J Physiol Gastrointest Liver Physiol. 2006 Apr;290(4):G813-26. doi: 10.1152/ajpgi.00306.2005. Epub 2005 Dec 8. Am J Physiol Gastrointest Liver Physiol. 2006. PMID: 16339297 Free article.
Prolactin stimulates the proliferation of normal female cholangiocytes by differential regulation of Ca2+-dependent PKC isoforms.
Taffetani S, Glaser S, Francis H, DeMorrow S, Ueno Y, Alvaro D, Marucci L, Marzioni M, Fava G, Venter J, Vaculin S, Vaculin B, Lam IP, Lee VH, Gaudio E, Carpino G, Benedetti A, Alpini G. Taffetani S, et al. Among authors: alvaro d. BMC Physiol. 2007 Jul 19;7:6. doi: 10.1186/1472-6793-7-6. BMC Physiol. 2007. PMID: 17640386 Free PMC article.
Cholangiocyte proliferation and liver fibrosis.
Glaser SS, Gaudio E, Miller T, Alvaro D, Alpini G. Glaser SS, et al. Among authors: alvaro d. Expert Rev Mol Med. 2009 Feb 25;11:e7. doi: 10.1017/S1462399409000994. Expert Rev Mol Med. 2009. PMID: 19239726 Free PMC article. Review.
After damage of large bile ducts by gamma-aminobutyric acid, small ducts replenish the biliary tree by amplification of calcium-dependent signaling and de novo acquisition of large cholangiocyte phenotypes.
Mancinelli R, Franchitto A, Gaudio E, Onori P, Glaser S, Francis H, Venter J, Demorrow S, Carpino G, Kopriva S, White M, Fava G, Alvaro D, Alpini G. Mancinelli R, et al. Among authors: alvaro d. Am J Pathol. 2010 Apr;176(4):1790-800. doi: 10.2353/ajpath.2010.090677. Epub 2010 Feb 25. Am J Pathol. 2010. PMID: 20185575 Free PMC article.
344 results