Pouwels J - Search Results

1

Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint.

Salmela AL, Pouwels J, Varis A, Kukkonen AM, Toivonen P, Halonen PK, Perälä M, Kallioniemi O, Gorbsky GJ, Kallio MJ. Salmela AL, et al. Among authors: pouwels j. Carcinogenesis. 2009 Jun;30(6):1032-40. doi: 10.1093/carcin/bgp101. Epub 2009 Apr 24. Carcinogenesis. 2009. PMID: 19395653 Free PMC article.

2

Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1.

Pouwels J, Kukkonen AM, Lan W, Daum JR, Gorbsky GJ, Stukenberg T, Kallio MJ. Pouwels J, et al. Cell Cycle. 2007 Jul 1;6(13):1579-85. doi: 10.4161/cc.6.13.4442. Epub 2007 May 16. Cell Cycle. 2007. PMID: 17617734

3

The flavonoid eupatorin inactivates the mitotic checkpoint leading to polyploidy and apoptosis.

Salmela AL, Pouwels J, Kukkonen-Macchi A, Waris S, Toivonen P, Jaakkola K, Mäki-Jouppila J, Kallio L, Kallio MJ. Salmela AL, et al. Among authors: pouwels j. Exp Cell Res. 2012 Mar 10;318(5):578-92. doi: 10.1016/j.yexcr.2011.12.014. Epub 2011 Dec 29. Exp Cell Res. 2012. PMID: 22227008

4

Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases.

Salmela AL, Pouwels J, Mäki-Jouppila J, Kohonen P, Toivonen P, Kallio L, Kallio M. Salmela AL, et al. Among authors: pouwels j. Carcinogenesis. 2013 Feb;34(2):436-45. doi: 10.1093/carcin/bgs339. Epub 2012 Oct 26. Carcinogenesis. 2013. PMID: 23104179

5

Perturbation of Incenp function impedes anaphase chromatid movements and chromosomal passenger protein flux at centromeres.

Ahonen LJ, Kukkonen AM, Pouwels J, Bolton MA, Jingle CD, Stukenberg PT, Kallio MJ. Ahonen LJ, et al. Among authors: pouwels j. Chromosoma. 2009 Feb;118(1):71-84. doi: 10.1007/s00412-008-0178-0. Epub 2008 Sep 11. Chromosoma. 2009. PMID: 18784935 Free PMC article.

6

High frequency of TTK mutations in microsatellite-unstable colorectal cancer and evaluation of their effect on spindle assembly checkpoint.

Niittymäki I, Gylfe A, Laine L, Laakso M, Lehtonen HJ, Kondelin J, Tolvanen J, Nousiainen K, Pouwels J, Järvinen H, Nuorva K, Mecklin JP, Mäkinen M, Ristimäki A, Ørntoft TF, Hautaniemi S, Karhu A, Kallio MJ, Aaltonen LA. Niittymäki I, et al. Among authors: pouwels j. Carcinogenesis. 2011 Mar;32(3):305-11. doi: 10.1093/carcin/bgq272. Epub 2010 Dec 16. Carcinogenesis. 2011. PMID: 21163887

7

Loss of p38gamma MAPK induces pleiotropic mitotic defects and massive cell death.

Kukkonen-Macchi A, Sicora O, Kaczynska K, Oetken-Lindholm C, Pouwels J, Laine L, Kallio MJ. Kukkonen-Macchi A, et al. Among authors: pouwels j. J Cell Sci. 2011 Jan 15;124(Pt 2):216-27. doi: 10.1242/jcs.068254. Epub 2010 Dec 15. J Cell Sci. 2011. PMID: 21172807

8

Spatio-temporal composition of the mitotic Chromosomal Passenger Complex detected using in situ proximity ligation assay.

Vuoriluoto M, Laine LJ, Saviranta P, Pouwels J, Kallio MJ. Vuoriluoto M, et al. Among authors: pouwels j. Mol Oncol. 2011 Feb;5(1):105-11. doi: 10.1016/j.molonc.2010.10.002. Epub 2010 Oct 16. Mol Oncol. 2011. PMID: 21051298 Free PMC article.

9

SHARPIN is an endogenous inhibitor of β1-integrin activation.

Rantala JK, Pouwels J, Pellinen T, Veltel S, Laasola P, Mattila E, Potter CS, Duffy T, Sundberg JP, Kallioniemi O, Askari JA, Humphries MJ, Parsons M, Salmi M, Ivaska J. Rantala JK, et al. Among authors: pouwels j. Nat Cell Biol. 2011 Sep 25;13(11):1315-24. doi: 10.1038/ncb2340. Nat Cell Biol. 2011. PMID: 21947080 Free PMC article.

10

Negative regulators of integrin activity.

Pouwels J, Nevo J, Pellinen T, Ylänne J, Ivaska J. Pouwels J, et al. J Cell Sci. 2012 Jul 15;125(Pt 14):3271-80. doi: 10.1242/jcs.093641. Epub 2012 Jul 20. J Cell Sci. 2012. PMID: 22822081

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