Hu CC - Search Results

1

XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells.

Hu CC, Dougan SK, McGehee AM, Love JC, Ploegh HL. Hu CC, et al. EMBO J. 2009 Jun 3;28(11):1624-36. doi: 10.1038/emboj.2009.117. Epub 2009 Apr 30. EMBO J. 2009. PMID: 19407814 Free PMC article.

2

XBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis.

McGehee AM, Dougan SK, Klemm EJ, Shui G, Park B, Kim YM, Watson N, Wenk MR, Ploegh HL, Hu CC. McGehee AM, et al. Among authors: hu cc. J Immunol. 2009 Sep 15;183(6):3690-9. doi: 10.4049/jimmunol.0900953. Epub 2009 Aug 26. J Immunol. 2009. PMID: 19710472 Free PMC article.

3

Profiling antibody responses by multiparametric analysis of primary B cells.

Story CM, Papa E, Hu CC, Ronan JL, Herlihy K, Ploegh HL, Love JC. Story CM, et al. Among authors: hu cc. Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17902-7. doi: 10.1073/pnas.0805470105. Epub 2008 Nov 12. Proc Natl Acad Sci U S A. 2008. PMID: 19004776 Free PMC article.

4

Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes.

Hu CC, Dougan SK, Winter SV, Paton AW, Paton JC, Ploegh HL. Hu CC, et al. J Exp Med. 2009 Oct 26;206(11):2429-40. doi: 10.1084/jem.20090782. Epub 2009 Oct 6. J Exp Med. 2009. PMID: 19808260 Free PMC article.

5

Derlin-2-deficient mice reveal an essential role for protein dislocation in chondrocytes.

Dougan SK, Hu CC, Paquet ME, Greenblatt MB, Kim J, Lilley BN, Watson N, Ploegh HL. Dougan SK, et al. Among authors: hu cc. Mol Cell Biol. 2011 Mar;31(6):1145-59. doi: 10.1128/MCB.00967-10. Epub 2011 Jan 10. Mol Cell Biol. 2011. PMID: 21220515 Free PMC article.

6

IgG1+ ovalbumin-specific B-cell transnuclear mice show class switch recombination in rare allelically included B cells.

Dougan SK, Ogata S, Hu CC, Grotenbreg GM, Guillen E, Jaenisch R, Ploegh HL. Dougan SK, et al. Among authors: hu cc. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13739-44. doi: 10.1073/pnas.1210273109. Epub 2012 Aug 6. Proc Natl Acad Sci U S A. 2012. PMID: 22869725 Free PMC article.

7

Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization.

Tang CH, Chang S, Paton AW, Paton JC, Gabrilovich DI, Ploegh HL, Del Valle JR, Hu CC. Tang CH, et al. Among authors: hu cc. J Cell Biol. 2018 May 7;217(5):1739-1755. doi: 10.1083/jcb.201709137. Epub 2018 Mar 6. J Cell Biol. 2018. PMID: 29511123 Free PMC article.

8

Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival.

Tang CH, Ranatunga S, Kriss CL, Cubitt CL, Tao J, Pinilla-Ibarz JA, Del Valle JR, Hu CC. Tang CH, et al. Among authors: hu cc. J Clin Invest. 2014 Jun;124(6):2585-98. doi: 10.1172/JCI73448. Epub 2014 May 8. J Clin Invest. 2014. PMID: 24812669 Free PMC article.

9

Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival.

Tavernier SJ, Osorio F, Vandersarren L, Vetters J, Vanlangenakker N, Van Isterdael G, Vergote K, De Rycke R, Parthoens E, van de Laar L, Iwawaki T, Del Valle JR, Hu CC, Lambrecht BN, Janssens S. Tavernier SJ, et al. Among authors: hu cc. Nat Cell Biol. 2017 Jun;19(6):698-710. doi: 10.1038/ncb3518. Epub 2017 May 1. Nat Cell Biol. 2017. PMID: 28459443 Free PMC article.

10

Inhibition of the IRE-1α/XBP-1 pathway prevents chronic GVHD and preserves the GVL effect in mice.

Schutt SD, Wu Y, Tang CH, Bastian D, Nguyen H, Sofi MH, Zhang M, Liu C, Helke K, Wilson C, Schnapp LM, Del Valle JR, Hu CC, Yu XZ. Schutt SD, et al. Among authors: hu cc. Blood Adv. 2018 Feb 27;2(4):414-427. doi: 10.1182/bloodadvances.2017009068. Blood Adv. 2018. PMID: 29483082 Free PMC article.

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