Melvin LS - Search Results

1

Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1.

Monovich L, Koch KA, Burgis R, Osimboni E, Mann T, Wall D, Gao J, Feng Y, Vega RB, Turner BA, Hood DB, Law A, Papst PJ, Koditek D, Chapo JA, Reid BG, Melvin LS, Pagratis NC, McKinsey TA. Monovich L, et al. Among authors: melvin ls. Biochim Biophys Acta. 2009 May;1789(5):422-31. doi: 10.1016/j.bbagrm.2009.04.001. Epub 2009 May 3. Biochim Biophys Acta. 2009. PMID: 19414071

2

A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway.

Bush E, Fielitz J, Melvin L, Martinez-Arnold M, McKinsey TA, Plichta R, Olson EN. Bush E, et al. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2870-5. doi: 10.1073/pnas.0308723101. Epub 2004 Feb 19. Proc Natl Acad Sci U S A. 2004. PMID: 14976250 Free PMC article.

3

(+)-1-(3S,4R)-[3-(4-phenylbenzyl)-4-hydroxychroman-7-yl]cyclopentane carboxylic acid, a highly potent, selective leukotriene B4 antagonist with oral activity in the murine collagen-induced arthritis model.

Koch K, Melvin LS Jr, Reiter LA, Biggers MS, Showell HJ, Griffiths RJ, Pettipher ER, Cheng JB, Milici AJ, Breslow R, et al. Koch K, et al. Among authors: melvin ls jr. J Med Chem. 1994 Sep 30;37(20):3197-9. doi: 10.1021/jm00046a001. J Med Chem. 1994. PMID: 7932545 No abstract available.

4

Structure-activity relationships of tricyclic and nonclassical bicyclic cannabinoids.

Melvin LS, Johnson MR. Melvin LS, et al. NIDA Res Monogr. 1987;79:31-47. NIDA Res Monogr. 1987. PMID: 3125479 Review. No abstract available.

5

Conformational analysis of the prototype nonclassical cannabinoid CP-47,497, using 2D NMR and computer molecular modeling.

Xie XQ, Yang DP, Melvin LS, Makriyannis A. Xie XQ, et al. Among authors: melvin ls. J Med Chem. 1994 May 13;37(10):1418-26. doi: 10.1021/jm00036a006. J Med Chem. 1994. PMID: 8182700

6

Structure-activity relationships defining the ACD-tricyclic cannabinoids: cannabinoid receptor binding and analgesic activity.

Melvin LS, Milne GM, Johnson MR, Wilken GH, Howlett AC. Melvin LS, et al. Drug Des Discov. 1995 Nov;13(2):155-66. Drug Des Discov. 1995. PMID: 8872458

7

The conformational properties of the highly selective cannabinoid receptor ligand CP-55,940.

Xie XQ, Melvin LS, Makriyannis A. Xie XQ, et al. Among authors: melvin ls. J Biol Chem. 1996 May 3;271(18):10640-7. doi: 10.1074/jbc.271.18.10640. J Biol Chem. 1996. PMID: 8631869 Free article.

8

Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs.

Melvin LS, Milne GM, Johnson MR, Subramaniam B, Wilken GH, Howlett AC. Melvin LS, et al. Mol Pharmacol. 1993 Nov;44(5):1008-15. Mol Pharmacol. 1993. PMID: 8246904

9

A cannabinoid derived prototypical analgesic.

Melvin LS, Johnson MR, Harbert CA, Milne GM, Weissman A. Melvin LS, et al. J Med Chem. 1984 Jan;27(1):67-71. doi: 10.1021/jm00367a013. J Med Chem. 1984. PMID: 6690685

10

Structural studies leading to the discovery of a cannabinoid binding site.

Johnson M, Devane W, Howlett A, Melvin L, Milne G. Johnson M, et al. NIDA Res Monogr. 1988;90:129-35. NIDA Res Monogr. 1988. PMID: 3151919 Review. No abstract available.

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