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Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.
Orozco G, Hinks A, Eyre S, Ke X, Gibbons LJ, Bowes J, Flynn E, Martin P; Wellcome Trust Case Control Consortium; YEAR consortium; Wilson AG, Bax DE, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Thomson W, Barton A, Worthington J. Orozco G, et al. Among authors: flynn e. Hum Mol Genet. 2009 Jul 15;18(14):2693-9. doi: 10.1093/hmg/ddp193. Epub 2009 May 5. Hum Mol Genet. 2009. PMID: 19417005 Free PMC article.
Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes.
Barton A, Eyre S, Ke X, Hinks A, Bowes J, Flynn E, Martin P; YEAR Consortium; BIRAC Consortium; Wilson AG, Morgan AW, Emery P, Steer S, Hocking LJ, Reid DM, Harrison P, Wordsworth P, Thomson W, Worthington J. Barton A, et al. Among authors: flynn e. Hum Mol Genet. 2009 Jul 1;18(13):2518-22. doi: 10.1093/hmg/ddp177. Epub 2009 Apr 9. Hum Mol Genet. 2009. PMID: 19359276 Free PMC article.
Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis.
Hinks A, Martin P, Flynn E, Eyre S, Packham J, Barton A; Childhood Arthritis Prospective Study (CAPS), UKRAG Consortium, BSPAR study group; Worthington J, Thomson W. Hinks A, et al. Among authors: flynn e. Ann Rheum Dis. 2010 Dec;69(12):2169-72. doi: 10.1136/ard.2009.126938. Epub 2010 Jul 20. Ann Rheum Dis. 2010. PMID: 20647273 Free PMC article.
Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease.
Eyre S, Hinks A, Bowes J, Flynn E, Martin P, Wilson AG, Morgan AW, Emery P, Steer S, Hocking LJ, Reid DM, Harrison P, Wordsworth P; Yorkshire Early Arthritis Consortium; Biologics in RA Control Consortium; Thomson W, Worthington J, Barton A. Eyre S, et al. Among authors: flynn e. Arthritis Res Ther. 2010;12(5):R175. doi: 10.1186/ar3139. Epub 2010 Sep 20. Arthritis Res Ther. 2010. PMID: 20854658 Free PMC article.
Seven newly identified loci for autoimmune thyroid disease.
Cooper JD, Simmonds MJ, Walker NM, Burren O, Brand OJ, Guo H, Wallace C, Stevens H, Coleman G; Wellcome Trust Case Control Consortium; Franklyn JA, Todd JA, Gough SC. Cooper JD, et al. Hum Mol Genet. 2012 Dec 1;21(23):5202-8. doi: 10.1093/hmg/dds357. Epub 2012 Aug 24. Hum Mol Genet. 2012. PMID: 22922229 Free PMC article.
Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population.
Morgan AW, Thomson W, Martin SG; Yorkshire Early Arthritis Register Consortium; Carter AM; UK Rheumatoid Arthritis Genetics Consortium; Erlich HA, Barton A, Hocking L, Reid DM, Harrison P, Wordsworth P, Steer S, Worthington J, Emery P, Wilson AG, Barrett JH. Morgan AW, et al. Arthritis Rheum. 2009 Sep;60(9):2565-76. doi: 10.1002/art.24752. Arthritis Rheum. 2009. PMID: 19714585 Free article.
The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register.
Plant D, Thomson W, Lunt M, Flynn E, Martin P, Eyre S, Farragher T, Bunn D, Worthington J, Symmons D, Barton A. Plant D, et al. Among authors: flynn e. Rheumatology (Oxford). 2011 Jan;50(1):78-84. doi: 10.1093/rheumatology/keq032. Epub 2010 Mar 10. Rheumatology (Oxford). 2011. PMID: 20219786 Free PMC article.
573 results