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Discovery of potent, selective, and orally active carboxylic acid based inhibitors of matrix metalloproteinase-13.
J Med Chem. 2009 Jun 11;52(11):3523-38. doi: 10.1021/jm801394m.
J Med Chem. 2009.
PMID: 19422229
Leukotriene biosynthesis inhibition by aryl and aroyl substituted naphthoquinones.
Roland DM, Macchia WM, Grim KS, Kimble EF, White DH, Kowalski TJ.
Roland DM, et al.
Agents Actions. 1991 Sep;34(1-2):145-7. doi: 10.1007/BF01993262.
Agents Actions. 1991.
PMID: 1665288
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Inhibition of LTB4 biosynthesis in situ by CGS 23885, a potent 5-lipoxygenase inhibitor, correlates with its pleural fluid concentrations in an experimentally induced rat pleurisy model.
Raychaudhuri A, Chertock H, Chovan J, Jones LS, Kimble EF, Kowalski TJ, Peppard J, White DH, Satoh Y, Roland D.
Raychaudhuri A, et al.
Naunyn Schmiedebergs Arch Pharmacol. 1997 Apr;355(4):470-4. doi: 10.1007/pl00004971.
Naunyn Schmiedebergs Arch Pharmacol. 1997.
PMID: 9109363
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The effect of FUT-175 (Nafamstat Mesilate) on C3a, C4a and C5a generation in vitro and inflammatory reactions in vivo.
Issekutz AC, Roland DM, Patrick RA.
Issekutz AC, et al. Among authors: roland dm.
Int J Immunopharmacol. 1990;12(1):1-9. doi: 10.1016/0192-0561(90)90062-r.
Int J Immunopharmacol. 1990.
PMID: 2303313
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Structural relationships in the inhibition of [3H]tryptamine binding to rat brain membranes in vitro by phenylalkylamines.
Martin LL, Roland DM, Neale RF, Wood PL.
Martin LL, et al. Among authors: roland dm.
Eur J Pharmacol. 1986 Dec 2;132(1):53-5. doi: 10.1016/0014-2999(86)90008-7.
Eur J Pharmacol. 1986.
PMID: 3816964
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