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Probing the multifactorial basis of Plasmodium falciparum quinine resistance: evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE.
Nkrumah LJ, Riegelhaupt PM, Moura P, Johnson DJ, Patel J, Hayton K, Ferdig MT, Wellems TE, Akabas MH, Fidock DA. Nkrumah LJ, et al. Among authors: ferdig mt. Mol Biochem Parasitol. 2009 Jun;165(2):122-31. doi: 10.1016/j.molbiopara.2009.01.011. Epub 2009 Jan 30. Mol Biochem Parasitol. 2009. PMID: 19428659 Free PMC article.
Plasmodium falciparum Na+/H+ exchanger activity and quinine resistance.
Bennett TN, Patel J, Ferdig MT, Roepe PD. Bennett TN, et al. Among authors: ferdig mt. Mol Biochem Parasitol. 2007 May;153(1):48-58. doi: 10.1016/j.molbiopara.2007.01.018. Epub 2007 Feb 8. Mol Biochem Parasitol. 2007. PMID: 17353059 Free PMC article.
Mutations and/or overexpression of a P. falciparum multidrug resistance gene homologue (pfmdr1) may further modify or tailor the degree of quinoline drug resistance. Recently [Ferdig MT, Cooper RA, Mu JB, et al. Dissecting the loci of low-level quinine resistance in …
Mutations and/or overexpression of a P. falciparum multidrug resistance gene homologue (pfmdr1) may further modify or tailor the degree of q …
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