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Disruption of CXCR4 enhances osteoclastogenesis and tumor growth in bone.
Hirbe AC, Rubin J, Uluçkan O, Morgan EA, Eagleton MC, Prior JL, Piwnica-Worms D, Weilbaecher KN. Hirbe AC, et al. Among authors: eagleton mc. Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):14062-7. doi: 10.1073/pnas.0705203104. Epub 2007 Aug 22. Proc Natl Acad Sci U S A. 2007. PMID: 17715292 Free PMC article.
APT102, a novel adpase, cooperates with aspirin to disrupt bone metastasis in mice.
Uluçkan O, Eagleton MC, Floyd DH, Morgan EA, Hirbe AC, Kramer M, Dowland N, Prior JL, Piwnica-Worms D, Jeong SS, Chen R, Weilbaecher K. Uluçkan O, et al. Among authors: eagleton mc. J Cell Biochem. 2008 Jul 1;104(4):1311-23. doi: 10.1002/jcb.21709. J Cell Biochem. 2008. PMID: 18260128 Free PMC article.
The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling.
Su X, Floyd DH, Hughes A, Xiang J, Schneider JG, Uluckan O, Heller E, Deng H, Zou W, Craft CS, Wu K, Hirbe AC, Grabowska D, Eagleton MC, Townsley S, Collins L, Piwnica-Worms D, Steinberg TH, Novack DV, Conley PB, Hurchla MA, Rogers M, Weilbaecher KN. Su X, et al. Among authors: eagleton mc. J Clin Invest. 2012 Oct;122(10):3579-92. doi: 10.1172/JCI38576. Epub 2012 Sep 17. J Clin Invest. 2012. PMID: 22996695 Free PMC article.