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Isolation, structure, and antibacterial activity of philipimycin, a thiazolyl peptide discovered from Actinoplanes philippinensis MA7347.
Zhang C, Occi J, Masurekar P, Barrett JF, Zink DL, Smith S, Onishi R, Ha S, Salazar O, Genilloud O, Basilio A, Vicente F, Gill C, Hickey EJ, Dorso K, Motyl M, Singh SB. Zhang C, et al. Among authors: barrett jf. J Am Chem Soc. 2008 Sep 10;130(36):12102-10. doi: 10.1021/ja803183u. Epub 2008 Aug 13. J Am Chem Soc. 2008. PMID: 18698773
Platensimycin is a selective FabF inhibitor with potent antibiotic properties.
Wang J, Soisson SM, Young K, Shoop W, Kodali S, Galgoci A, Painter R, Parthasarathy G, Tang YS, Cummings R, Ha S, Dorso K, Motyl M, Jayasuriya H, Ondeyka J, Herath K, Zhang C, Hernandez L, Allocco J, Basilio A, Tormo JR, Genilloud O, Vicente F, Pelaez F, Colwell L, Lee SH, Michael B, Felcetto T, Gill C, Silver LL, Hermes JD, Bartizal K, Barrett J, Schmatz D, Becker JW, Cully D, Singh SB. Wang J, et al. Among authors: barrett j. Nature. 2006 May 18;441(7091):358-61. doi: 10.1038/nature04784. Nature. 2006. PMID: 16710421
Isolation and structure elucidation of thiazomycin- a potent thiazolyl peptide antibiotic from Amycolatopsis fastidiosa.
Jayasuriya H, Herath K, Ondeyka JG, Zhang C, Zink DL, Brower M, Gailliot FP, Greene J, Birdsall G, Venugopal J, Ushio M, Burgess B, Russotti G, Walker A, Hesse M, Seeley A, Junker B, Connors N, Salazar O, Genilloud O, Liu K, Masurekar P, Barrett JF, Singh SB. Jayasuriya H, et al. Among authors: barrett jf. J Antibiot (Tokyo). 2007 Sep;60(9):554-64. doi: 10.1038/ja.2007.70. J Antibiot (Tokyo). 2007. PMID: 17917238
Novel inhibitors of bacterial two-component systems with gram positive antibacterial activity: pharmacophore identification based on the screening hit closantel.
Hlasta DJ, Demers JP, Foleno BD, Fraga-Spano SA, Guan J, Hilliard JJ, Macielag MJ, Ohemeng KA, Sheppard CM, Sui Z, Webb GC, Weidner-Wells MA, Werblood H, Barrett JF. Hlasta DJ, et al. Among authors: barrett jf. Bioorg Med Chem Lett. 1998 Jul 21;8(14):1923-8. doi: 10.1016/s0960-894x(98)00326-6. Bioorg Med Chem Lett. 1998. PMID: 9873460
Biaryl isoxazolinone antibacterial agents.
Quesnelle CA, Gill P, Roy S, Dodier M, Marinier A, Martel A, Snyder LB, D'Andrea SV, Bronson JJ, Frosco M, Beaulieu D, Warr GA, Denbleyker KL, Stickle TM, Yang H, Chaniewski SE, Ferraro CA, Taylor D, Russell JW, Santone KS, Clarke J, Drain RL, Knipe JO, Mosure K, Barrett JF. Quesnelle CA, et al. Among authors: barrett jf. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2728-33. doi: 10.1016/j.bmcl.2005.04.003. Bioorg Med Chem Lett. 2005. PMID: 15869878
4,418 results