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Abeta43 is more frequent than Abeta40 in amyloid plaque cores from Alzheimer disease brains.
J Neurochem. 2009 Jul;110(2):697-706. doi: 10.1111/j.1471-4159.2009.06170.x. Epub 2009 May 15.
J Neurochem. 2009.
PMID: 19457079
Free article.
Rat brain gamma-secretase activity is highly influenced by detergents.
Frånberg J, Welander H, Aoki M, Winblad B, Tjernberg LO, Frykman S.
Frånberg J, et al.
Biochemistry. 2007 Jun 26;46(25):7647-54. doi: 10.1021/bi0621258. Epub 2007 May 31.
Biochemistry. 2007.
PMID: 17536783
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Active gamma-secretase is localized to detergent-resistant membranes in human brain.
Hur JY, Welander H, Behbahani H, Aoki M, Frånberg J, Winblad B, Frykman S, Tjernberg LO.
Hur JY, et al. Among authors: franberg j.
FEBS J. 2008 Mar;275(6):1174-87. doi: 10.1111/j.1742-4658.2008.06278.x. Epub 2008 Feb 6.
FEBS J. 2008.
PMID: 18266764
Free article.
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Affinity pulldown of γ-secretase and associated proteins from human and rat brain.
Teranishi Y, Hur JY, Welander H, Frånberg J, Aoki M, Winblad B, Frykman S, Tjernberg LO.
Teranishi Y, et al. Among authors: franberg j.
J Cell Mol Med. 2010 Nov;14(11):2675-86. doi: 10.1111/j.1582-4934.2009.00907.x.
J Cell Mol Med. 2010.
PMID: 19754663
Free PMC article.
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The large hydrophilic loop of presenilin 1 is important for regulating gamma-secretase complex assembly and dictating the amyloid beta peptide (Abeta) Profile without affecting Notch processing.
Wanngren J, Frånberg J, Svensson AI, Laudon H, Olsson F, Winblad B, Liu F, Näslund J, Lundkvist J, Karlström H.
Wanngren J, et al. Among authors: franberg j.
J Biol Chem. 2010 Mar 19;285(12):8527-36. doi: 10.1074/jbc.M109.055590. Epub 2010 Jan 27.
J Biol Chem. 2010.
PMID: 20106965
Free PMC article.
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Synaptic and endosomal localization of active gamma-secretase in rat brain.
Frykman S, Hur JY, Frånberg J, Aoki M, Winblad B, Nahalkova J, Behbahani H, Tjernberg LO.
Frykman S, et al. Among authors: franberg j.
PLoS One. 2010 Jan 28;5(1):e8948. doi: 10.1371/journal.pone.0008948.
PLoS One. 2010.
PMID: 20126630
Free PMC article.
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gamma-Secretase dependent production of intracellular domains is reduced in adult compared to embryonic rat brain membranes.
Frånberg J, Karlström H, Winblad B, Tjernberg LO, Frykman S.
Frånberg J, et al.
PLoS One. 2010 Mar 19;5(3):e9772. doi: 10.1371/journal.pone.0009772.
PLoS One. 2010.
PMID: 20333303
Free PMC article.
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Minor contribution of presenilin 2 for γ-secretase activity in mouse embryonic fibroblasts and adult mouse brain.
Frånberg J, Svensson AI, Winblad B, Karlström H, Frykman S.
Frånberg J, et al.
Biochem Biophys Res Commun. 2011 Jan 7;404(1):564-8. doi: 10.1016/j.bbrc.2010.12.029. Epub 2010 Dec 10.
Biochem Biophys Res Commun. 2011.
PMID: 21146496
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