Umezawa K - Search Results

1

Antitumor effects of dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, in human liver cancer cells are mediated through a reactive oxygen species-dependent mechanism.

Lampiasi N, Azzolina A, D'Alessandro N, Umezawa K, McCubrey JA, Montalto G, Cervello M. Lampiasi N, et al. Among authors: umezawa k. Mol Pharmacol. 2009 Aug;76(2):290-300. doi: 10.1124/mol.109.055418. Epub 2009 May 20. Mol Pharmacol. 2009. PMID: 19461054

2

Induction of thyroid cancer cell apoptosis by a novel nuclear factor kappaB inhibitor, dehydroxymethylepoxyquinomicin.

Starenki DV, Namba H, Saenko VA, Ohtsuru A, Maeda S, Umezawa K, Yamashita S. Starenki DV, et al. Among authors: umezawa k. Clin Cancer Res. 2004 Oct 15;10(20):6821-9. doi: 10.1158/1078-0432.CCR-04-0463. Clin Cancer Res. 2004. PMID: 15501958

3

Dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, induces apoptosis in multiple myeloma cells in an IkappaBalpha-independent manner.

Tatetsu H, Okuno Y, Nakamura M, Matsuno F, Sonoki T, Taniguchi I, Uneda S, Umezawa K, Mitsuya H, Hata H. Tatetsu H, et al. Among authors: umezawa k. Mol Cancer Ther. 2005 Jul;4(7):1114-20. doi: 10.1158/1535-7163.MCT-04-0198. Mol Cancer Ther. 2005. PMID: 16020669

4

Chemosensitization and immunosensitization of resistant cancer cells to apoptosis and inhibition of metastasis by the specific NF-kappaB inhibitor DHMEQ.

Katsman A, Umezawa K, Bonavida B. Katsman A, et al. Among authors: umezawa k. Curr Pharm Des. 2009;15(7):792-808. doi: 10.2174/138161209787582156. Curr Pharm Des. 2009. PMID: 19275643 Review.

5

Dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, prevents inflammatory injury induced by interferon-gamma and histamine in NCTC 2544 keratinocytes.

Cardile V, Libra M, Caggia S, Frasca G, Umezawa K, Stivala F, Mazzarino MC, Bevelacqua Y, Coco M, Malaponte G. Cardile V, et al. Among authors: umezawa k. Clin Exp Pharmacol Physiol. 2010 Jul;37(7):679-83. doi: 10.1111/j.1440-1681.2010.05375.x. Epub 2010 Mar 12. Clin Exp Pharmacol Physiol. 2010. PMID: 20337659

6

Novel approaches to target cancer initiating cells-eliminating the root of the cancer.

McCubrey JA, Abrams SL, Umezawa K, Cocco L, Martelli AM, Franklin RA, Chappell WH, Steelman LS. McCubrey JA, et al. Among authors: umezawa k. Adv Biol Regul. 2012 Jan;52(1):249-64. doi: 10.1016/j.advenzreg.2011.09.011. Adv Biol Regul. 2012. PMID: 21930143 Review. No abstract available.

7

The novel NF-κB inhibitor DHMEQ synergizes with celecoxib to exert antitumor effects on human liver cancer cells by a ROS-dependent mechanism.

Lampiasi N, Azzolina A, Umezawa K, Montalto G, McCubrey JA, Cervello M. Lampiasi N, et al. Among authors: umezawa k. Cancer Lett. 2012 Sep 1;322(1):35-44. doi: 10.1016/j.canlet.2012.02.008. Epub 2012 Feb 16. Cancer Lett. 2012. PMID: 22343223

8

Pleiotropic potential of dehydroxymethylepoxyquinomicin for NF-κB suppression via reactive oxygen species and unfolded protein response.

Nakajima S, Kato H, Gu L, Takahashi S, Johno H, Umezawa K, Kitamura M. Nakajima S, et al. Among authors: umezawa k. J Immunol. 2013 Jun 15;190(12):6559-69. doi: 10.4049/jimmunol.1300155. Epub 2013 May 20. J Immunol. 2013. PMID: 23690471

9

Poly (ADP-ribose) polymerase inhibition synergizes with the NF-κB inhibitor DHMEQ to kill hepatocellular carcinoma cells.

Lampiasi N, Umezawa K, Montalto G, Cervello M. Lampiasi N, et al. Among authors: umezawa k. Biochim Biophys Acta. 2014 Nov;1843(11):2662-73. doi: 10.1016/j.bbamcr.2014.07.010. Epub 2014 Jul 26. Biochim Biophys Acta. 2014. PMID: 25072752 Free article.

10

Corrigendum to "poly (ADP-ribose) polymerase inhibition synergizes with the NF-κB inhibitor DHMEQ to kill hepatocellular carcinoma cells" [Biochim. Biophys. Acta 1853(12)(2015) 3224-3234].

Lampiasi N, Umezawa K, Montalto G, Cervello M. Lampiasi N, et al. Among authors: umezawa k. Biochim Biophys Acta Mol Cell Res. 2018 Jul;1865(7):1023. doi: 10.1016/j.bbamcr.2018.04.004. Epub 2018 Apr 21. Biochim Biophys Acta Mol Cell Res. 2018. PMID: 29685431 Free article. No abstract available.

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