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PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women.
Chen C, Wickenheisser J, Ewens KG, Ankener W, Legro RS, Dunaif A, McAllister JM, Spielman RS, Strauss JF 3rd. Chen C, et al. Among authors: wickenheisser j. Mol Hum Reprod. 2009 Aug;15(8):459-69. doi: 10.1093/molehr/gap035. Epub 2009 May 29. Mol Hum Reprod. 2009. PMID: 19482904 Free PMC article.
Increased transcription and increased messenger ribonucleic acid (mRNA) stability contribute to increased GATA6 mRNA abundance in polycystic ovary syndrome theca cells.
Ho CK, Wood JR, Stewart DR, Ewens K, Ankener W, Wickenheisser J, Nelson-Degrave V, Zhang Z, Legro RS, Dunaif A, McAllister JM, Spielman R, Strauss JF 3rd. Ho CK, et al. Among authors: wickenheisser j. J Clin Endocrinol Metab. 2005 Dec;90(12):6596-602. doi: 10.1210/jc.2005-0890. Epub 2005 Sep 13. J Clin Endocrinol Metab. 2005. PMID: 16159937
Alterations in mitogen-activated protein kinase kinase and extracellular regulated kinase signaling in theca cells contribute to excessive androgen production in polycystic ovary syndrome.
Nelson-Degrave VL, Wickenheisser JK, Hendricks KL, Asano T, Fujishiro M, Legro RS, Kimball SR, Strauss JF 3rd, McAllister JM. Nelson-Degrave VL, et al. Among authors: wickenheisser jk. Mol Endocrinol. 2005 Feb;19(2):379-90. doi: 10.1210/me.2004-0178. Epub 2004 Oct 28. Mol Endocrinol. 2005. PMID: 15514033
Valproate potentiates androgen biosynthesis in human ovarian theca cells.
Nelson-DeGrave VL, Wickenheisser JK, Cockrell JE, Wood JR, Legro RS, Strauss JF 3rd, McAllister JM. Nelson-DeGrave VL, et al. Among authors: wickenheisser jk. Endocrinology. 2004 Feb;145(2):799-808. doi: 10.1210/en.2003-0940. Epub 2003 Oct 23. Endocrinology. 2004. PMID: 14576182
Human ovarian theca cells in culture.
Wickenheisser JK, Nelson-DeGrave VL, McAllister JM. Wickenheisser JK, et al. Trends Endocrinol Metab. 2006 Mar;17(2):65-71. doi: 10.1016/j.tem.2006.01.003. Epub 2006 Feb 7. Trends Endocrinol Metab. 2006. PMID: 16460956 Review.
11 results