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HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.
Daly AK, Donaldson PT, Bhatnagar P, Shen Y, Pe'er I, Floratos A, Daly MJ, Goldstein DB, John S, Nelson MR, Graham J, Park BK, Dillon JF, Bernal W, Cordell HJ, Pirmohamed M, Aithal GP, Day CP; DILIGEN Study; International SAE Consortium. Daly AK, et al. Among authors: pirmohamed m. Nat Genet. 2009 Jul;41(7):816-9. doi: 10.1038/ng.379. Epub 2009 May 31. Nat Genet. 2009. PMID: 19483685
Idiosyncratic drug reactions: a mechanistic evaluation of risk factors.
Park BK, Pirmohamed M, Kitteringham NR. Park BK, et al. Among authors: pirmohamed m. Br J Clin Pharmacol. 1992 Nov;34(5):377-95. doi: 10.1111/j.1365-2125.1992.tb05647.x. Br J Clin Pharmacol. 1992. PMID: 1467132 Free PMC article. Review. No abstract available.
The role of active metabolites in drug toxicity.
Pirmohamed M, Kitteringham NR, Park BK. Pirmohamed M, et al. Drug Saf. 1994 Aug;11(2):114-44. doi: 10.2165/00002018-199411020-00006. Drug Saf. 1994. PMID: 7945999 Review.
713 results