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Inhibition of sphingosine-1-phosphate lyase for the treatment of autoimmune disorders.
Bagdanoff JT, Donoviel MS, Nouraldeen A, Tarver J, Fu Q, Carlsen M, Jessop TC, Zhang H, Hazelwood J, Nguyen H, Baugh SD, Gardyan M, Terranova KM, Barbosa J, Yan J, Bednarz M, Layek S, Courtney LF, Taylor J, Digeorge-Foushee AM, Gopinathan S, Bruce D, Smith T, Moran L, O'Neill E, Kramer J, Lai Z, Kimball SD, Liu Q, Sun W, Yu S, Swaffield J, Wilson A, Main A, Carson KG, Oravecz T, Augeri DJ. Bagdanoff JT, et al. Among authors: bruce d. J Med Chem. 2009 Jul 9;52(13):3941-53. doi: 10.1021/jm900278w. J Med Chem. 2009. PMID: 19489538
Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes.
Goodwin NC, Ding ZM, Harrison BA, Strobel ED, Harris AL, Smith M, Thompson AY, Xiong W, Mseeh F, Bruce DJ, Diaz D, Gopinathan S, Li L, O'Neill E, Thiel M, Wilson AG, Carson KG, Powell DR, Rawlins DB. Goodwin NC, et al. Among authors: bruce dj. J Med Chem. 2017 Jan 26;60(2):710-721. doi: 10.1021/acs.jmedchem.6b01541. Epub 2017 Jan 17. J Med Chem. 2017. PMID: 28045524
Early toxicology signal generation in the mouse.
Kramer JA, O'Neill E, Phillips ME, Bruce D, Smith T, Albright MM, Bellum S, Gopinathan S, Heydorn WE, Liu X, Nouraldeen A, Payne BJ, Read R, Vogel P, Yu XQ, Wilson AG. Kramer JA, et al. Among authors: bruce d. Toxicol Pathol. 2010 Apr;38(3):452-71. doi: 10.1177/0192623310364025. Epub 2010 Mar 19. Toxicol Pathol. 2010. PMID: 20305093
Gold(III), Mercury(II), and Palladium(II) Complexes of a Series of Isomeric Bis(mono- and dialkoxyphenyl)pyridines: Introduction of Gold through Transmetalation and Catalysis.
McEllin AJ, Goult CA, Mohiuddin G, Curtis LJ, Tanner TFN, Whitwood AC, Lynam JM, Bruce DW. McEllin AJ, et al. Among authors: bruce dw. Inorg Chem. 2024 Apr 29;63(17):7589-7603. doi: 10.1021/acs.inorgchem.3c03791. Epub 2024 Apr 18. Inorg Chem. 2024. PMID: 38635870 Free PMC article.
Positive Impacts of Adolescent Involvement in Health Research: An Umbrella Review.
Warraitch A, Wacker C, Biju S, Lee M, Bruce D, Curran P, Khraisha Q, Hadfield K. Warraitch A, et al. Among authors: bruce d. J Adolesc Health. 2024 Apr 8:S1054-139X(24)00121-6. doi: 10.1016/j.jadohealth.2024.02.029. Online ahead of print. J Adolesc Health. 2024. PMID: 38597838 Free article. Review.
1,278 results