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Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations.
Am J Hum Genet. 2009 Jul;85(1):106-11. doi: 10.1016/j.ajhg.2009.06.002. Epub 2009 Jun 25.
Am J Hum Genet. 2009.
PMID: 19559399
Free PMC article.
Prevalence of loss-of-function FTO mutations in lean and obese individuals.
Meyre D, Proulx K, Kawagoe-Takaki H, Vatin V, Gutiérrez-Aguilar R, Lyon D, Ma M, Choquet H, Horber F, Van Hul W, Van Gaal L, Balkau B, Visvikis-Siest S, Pattou F, Farooqi IS, Saudek V, O'Rahilly S, Froguel P, Sedgwick B, Yeo GS.
Meyre D, et al. Among authors: kawagoe takaki h.
Diabetes. 2010 Jan;59(1):311-8. doi: 10.2337/db09-0703. Epub 2009 Oct 15.
Diabetes. 2010.
PMID: 19833892
Free PMC article.
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Correlation of receptor occupancy of metabotropic glutamate receptor subtype 1 (mGluR1) in mouse brain with in vivo activity of allosteric mGluR1 antagonists.
Suzuki G, Kawagoe-Takaki H, Inoue T, Kimura T, Hikichi H, Murai T, Satow A, Hata M, Maehara S, Ito S, Kawamoto H, Ozaki S, Ohta H.
Suzuki G, et al. Among authors: kawagoe takaki h.
J Pharmacol Sci. 2009 Jul;110(3):315-25. doi: 10.1254/jphs.09011fp. Epub 2009 Jun 19.
J Pharmacol Sci. 2009.
PMID: 19542684
Free article.
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Unique antipsychotic activities of the selective metabotropic glutamate receptor 1 allosteric antagonist 2-cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one.
Satow A, Suzuki G, Maehara S, Hikichi H, Murai T, Murai T, Kawagoe-Takaki H, Hata M, Ito S, Ozaki S, Kawamoto H, Ohta H.
Satow A, et al. Among authors: kawagoe takaki h.
J Pharmacol Exp Ther. 2009 Jul;330(1):179-90. doi: 10.1124/jpet.109.151118. Epub 2009 Apr 9.
J Pharmacol Exp Ther. 2009.
PMID: 19359526
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Pharmacological characterization of a new, orally active and potent allosteric metabotropic glutamate receptor 1 antagonist, 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide (FTIDC).
Suzuki G, Kimura T, Satow A, Kaneko N, Fukuda J, Hikichi H, Sakai N, Maehara S, Kawagoe-Takaki H, Hata M, Azuma T, Ito S, Kawamoto H, Ohta H.
Suzuki G, et al. Among authors: kawagoe takaki h.
J Pharmacol Exp Ther. 2007 Jun;321(3):1144-53. doi: 10.1124/jpet.106.116574. Epub 2007 Mar 14.
J Pharmacol Exp Ther. 2007.
PMID: 17360958
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Probing the secondary structure of salmon SmaI SINE RNA.
Kawagoe-Takaki H, Nameki N, Kajikawa M, Okada N.
Kawagoe-Takaki H, et al.
Gene. 2006 Jan 3;365:67-73. doi: 10.1016/j.gene.2005.09.027. Epub 2005 Dec 13.
Gene. 2006.
PMID: 16356664
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