Rameh LE - Search Results

1

AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.

Vasudevan KM, Barbie DA, Davies MA, Rabinovsky R, McNear CJ, Kim JJ, Hennessy BT, Tseng H, Pochanard P, Kim SY, Dunn IF, Schinzel AC, Sandy P, Hoersch S, Sheng Q, Gupta PB, Boehm JS, Reiling JH, Silver S, Lu Y, Stemke-Hale K, Dutta B, Joy C, Sahin AA, Gonzalez-Angulo AM, Lluch A, Rameh LE, Jacks T, Root DE, Lander ES, Mills GB, Hahn WC, Sellers WR, Garraway LA. Vasudevan KM, et al. Among authors: rameh le. Cancer Cell. 2009 Jul 7;16(1):21-32. doi: 10.1016/j.ccr.2009.04.012. Cancer Cell. 2009. PMID: 19573809 Free PMC article.

2

Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling.

Gewinner C, Wang ZC, Richardson A, Teruya-Feldstein J, Etemadmoghadam D, Bowtell D, Barretina J, Lin WM, Rameh L, Salmena L, Pandolfi PP, Cantley LC. Gewinner C, et al. Cancer Cell. 2009 Aug 4;16(2):115-25. doi: 10.1016/j.ccr.2009.06.006. Cancer Cell. 2009. PMID: 19647222 Free PMC article.

3

PIPPing on AKT1: How Many Phosphatases Does It Take to Turn off PI3K?

Toker A, Rameh L. Toker A, et al. Cancer Cell. 2015 Aug 10;28(2):143-5. doi: 10.1016/j.ccell.2015.07.010. Cancer Cell. 2015. PMID: 26267528 Free article.

4

Systemic elevation of PTEN induces a tumor-suppressive metabolic state.

Garcia-Cao I, Song MS, Hobbs RM, Laurent G, Giorgi C, de Boer VC, Anastasiou D, Ito K, Sasaki AT, Rameh L, Carracedo A, Vander Heiden MG, Cantley LC, Pinton P, Haigis MC, Pandolfi PP. Garcia-Cao I, et al. Cell. 2012 Mar 30;149(1):49-62. doi: 10.1016/j.cell.2012.02.030. Epub 2012 Mar 6. Cell. 2012. PMID: 22401813 Free PMC article.

5

Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.

Emerling BM, Hurov JB, Poulogiannis G, Tsukazawa KS, Choo-Wing R, Wulf GM, Bell EL, Shim HS, Lamia KA, Rameh LE, Bellinger G, Sasaki AT, Asara JM, Yuan X, Bullock A, Denicola GM, Song J, Brown V, Signoretti S, Cantley LC. Emerling BM, et al. Among authors: rameh le. Cell. 2013 Nov 7;155(4):844-57. doi: 10.1016/j.cell.2013.09.057. Cell. 2013. PMID: 24209622 Free PMC article.

6

AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve.

Er EE, Mendoza MC, Mackey AM, Rameh LE, Blenis J. Er EE, et al. Among authors: rameh le. Sci Signal. 2013 Jun 11;6(279):ra45. doi: 10.1126/scisignal.2004015. Sci Signal. 2013. PMID: 23757022 Free PMC article.

7

Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins.

Rameh LE, Chen CS, Cantley LC. Rameh LE, et al. Cell. 1995 Dec 1;83(5):821-30. doi: 10.1016/0092-8674(95)90195-7. Cell. 1995. PMID: 8521499 Free article.

8

The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradation.

Carricaburu V, Lamia KA, Lo E, Favereaux L, Payrastre B, Cantley LC, Rameh LE. Carricaburu V, et al. Among authors: rameh le. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9867-72. doi: 10.1073/pnas.1734038100. Epub 2003 Aug 1. Proc Natl Acad Sci U S A. 2003. PMID: 12897244 Free PMC article.

9

Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation.

Poliseno L, Salmena L, Riccardi L, Fornari A, Song MS, Hobbs RM, Sportoletti P, Varmeh S, Egia A, Fedele G, Rameh L, Loda M, Pandolfi PP. Poliseno L, et al. Sci Signal. 2010 Apr 13;3(117):ra29. doi: 10.1126/scisignal.2000594. Sci Signal. 2010. PMID: 20388916 Free PMC article.

10

Negative regulation of Vps34 by Cdk mediated phosphorylation.

Furuya T, Kim M, Lipinski M, Li J, Kim D, Lu T, Shen Y, Rameh L, Yankner B, Tsai LH, Yuan J. Furuya T, et al. Mol Cell. 2010 May 28;38(4):500-11. doi: 10.1016/j.molcel.2010.05.009. Mol Cell. 2010. PMID: 20513426 Free PMC article.

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