Hayashi R - Search Results

1

Human immunodeficiency virus type 1 nucleocapsid inhibitors impede trans infection in cellular and explant models and protect nonhuman primates from infection.

Wallace GS, Cheng-Mayer C, Schito ML, Fletcher P, Miller Jenkins LM, Hayashi R, Neurath AR, Appella E, Shattock RJ. Wallace GS, et al. Among authors: hayashi r. J Virol. 2009 Sep;83(18):9175-82. doi: 10.1128/JVI.00820-09. Epub 2009 Jul 8. J Virol. 2009. PMID: 19587055 Free PMC article.

2

Small-molecule inactivation of HIV-1 NCp7 by repetitive intracellular acyl transfer.

Miller Jenkins LM, Ott DE, Hayashi R, Coren LV, Wang D, Xu Q, Schito ML, Inman JK, Appella DH, Appella E. Miller Jenkins LM, et al. Among authors: hayashi r. Nat Chem Biol. 2010 Dec;6(12):887-9. doi: 10.1038/nchembio.456. Epub 2010 Oct 17. Nat Chem Biol. 2010. PMID: 20953192 Free PMC article.

3

Specificity of acyl transfer from 2-mercaptobenzamide thioesters to the HIV-1 nucleocapsid protein.

Miller Jenkins LM, Hara T, Durell SR, Hayashi R, Inman JK, Piquemal JP, Gresh N, Appella E. Miller Jenkins LM, et al. Among authors: hayashi r. J Am Chem Soc. 2007 Sep 12;129(36):11067-78. doi: 10.1021/ja071254o. Epub 2007 Aug 18. J Am Chem Soc. 2007. PMID: 17705474

4

Optimization of a cyclic peptide inhibitor of Ser/Thr phosphatase PPM1D (Wip1).

Hayashi R, Tanoue K, Durell SR, Chatterjee DK, Jenkins LM, Appella DH, Appella E. Hayashi R, et al. Biochemistry. 2011 May 31;50(21):4537-49. doi: 10.1021/bi101949t. Epub 2011 May 9. Biochemistry. 2011. PMID: 21528848 Free PMC article.

5

Targeting androgen receptor/Src complex impairs the aggressive phenotype of human fibrosarcoma cells.

Castoria G, Giovannelli P, Di Donato M, Hayashi R, Arra C, Appella E, Auricchio F, Migliaccio A. Castoria G, et al. Among authors: hayashi r. PLoS One. 2013 Oct 9;8(10):e76899. doi: 10.1371/journal.pone.0076899. eCollection 2013. PLoS One. 2013. PMID: 24130806 Free PMC article.

6

Targeting cancer stem cells with p53 modulators.

Zhang Z, Liu L, Gomez-Casal R, Wang X, Hayashi R, Appella E, Kopelovich L, DeLeo AB. Zhang Z, et al. Among authors: hayashi r. Oncotarget. 2016 Jul 19;7(29):45079-45093. doi: 10.18632/oncotarget.8650. Oncotarget. 2016. PMID: 27074569 Free PMC article.

7

Two distinct motifs within the p53 transactivation domain bind to the Taz2 domain of p300 and are differentially affected by phosphorylation.

Jenkins LM, Yamaguchi H, Hayashi R, Cherry S, Tropea JE, Miller M, Wlodawer A, Appella E, Mazur SJ. Jenkins LM, et al. Among authors: hayashi r. Biochemistry. 2009 Feb 17;48(6):1244-55. doi: 10.1021/bi801716h. Biochemistry. 2009. PMID: 19166313 Free PMC article.

8

Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.

Roy S, Musselman CA, Kachirskaia I, Hayashi R, Glass KC, Nix JC, Gozani O, Appella E, Kutateladze TG. Roy S, et al. Among authors: hayashi r. J Mol Biol. 2010 May 14;398(4):489-96. doi: 10.1016/j.jmb.2010.03.024. Epub 2010 Mar 20. J Mol Biol. 2010. PMID: 20307547 Free PMC article.

9

The MBT repeats of L3MBTL1 link SET8-mediated p53 methylation at lysine 382 to target gene repression.

West LE, Roy S, Lachmi-Weiner K, Hayashi R, Shi X, Appella E, Kutateladze TG, Gozani O. West LE, et al. Among authors: hayashi r. J Biol Chem. 2010 Nov 26;285(48):37725-32. doi: 10.1074/jbc.M110.139527. Epub 2010 Sep 24. J Biol Chem. 2010. PMID: 20870725 Free PMC article.

10

Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation.

Feng H, Jenkins LM, Durell SR, Hayashi R, Mazur SJ, Cherry S, Tropea JE, Miller M, Wlodawer A, Appella E, Bai Y. Feng H, et al. Among authors: hayashi r. Structure. 2009 Feb 13;17(2):202-10. doi: 10.1016/j.str.2008.12.009. Structure. 2009. PMID: 19217391 Free PMC article.

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