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PLK1 down-regulates parainfluenza virus 5 gene expression.
Sun D, Luthra P, Li Z, He B. Sun D, et al. Among authors: luthra p. PLoS Pathog. 2009 Jul;5(7):e1000525. doi: 10.1371/journal.ppat.1000525. Epub 2009 Jul 24. PLoS Pathog. 2009. PMID: 19629176 Free PMC article.
The V protein of mumps virus plays a critical role in pathogenesis.
Xu P, Luthra P, Li Z, Fuentes S, D'Andrea JA, Wu J, Rubin S, Rota PA, He B. Xu P, et al. Among authors: luthra p. J Virol. 2012 Feb;86(3):1768-76. doi: 10.1128/JVI.06019-11. Epub 2011 Nov 16. J Virol. 2012. PMID: 22090137 Free PMC article.
In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity.
Brown CS, Lee MS, Leung DW, Wang T, Xu W, Luthra P, Anantpadma M, Shabman RS, Melito LM, MacMillan KS, Borek DM, Otwinowski Z, Ramanan P, Stubbs AJ, Peterson DS, Binning JM, Tonelli M, Olson MA, Davey RA, Ready JM, Basler CF, Amarasinghe GK. Brown CS, et al. Among authors: luthra p. J Mol Biol. 2014 May 15;426(10):2045-58. doi: 10.1016/j.jmb.2014.01.010. Epub 2014 Feb 1. J Mol Biol. 2014. PMID: 24495995 Free PMC article.
Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses.
Chatterjee S, Luthra P, Esaulova E, Agapov E, Yen BC, Borek DM, Edwards MR, Mittal A, Jordan DS, Ramanan P, Moore ML, Pappu RV, Holtzman MJ, Artyomov MN, Basler CF, Amarasinghe GK, Leung DW. Chatterjee S, et al. Among authors: luthra p. Nat Microbiol. 2017 Jun 30;2:17101. doi: 10.1038/nmicrobiol.2017.101. Nat Microbiol. 2017. PMID: 28665409 Free PMC article.
115 results