Lay K - Search Results

1

Regulation of expression of the rat orthologue of mouse double minute 2 (MDM2) by H(2)O(2)-induced oxidative stress in neonatal rat cardiac myocytes.

Pikkarainen S, Kennedy RA, Marshall AK, Tham el L, Lay K, Kriz TA, Handa BS, Clerk A, Sugden PH. Pikkarainen S, et al. Among authors: lay k. J Biol Chem. 2009 Oct 2;284(40):27195-210. doi: 10.1074/jbc.M109.037887. Epub 2009 Jul 28. J Biol Chem. 2009. PMID: 19638633 Free PMC article.

2

The cardiomyocyte "redox rheostat": Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death.

Meijles DN, Zoumpoulidou G, Markou T, Rostron KA, Patel R, Lay K, Handa BS, Wong B, Sugden PH, Clerk A. Meijles DN, et al. Among authors: lay k. J Mol Cell Cardiol. 2019 Apr;129:118-129. doi: 10.1016/j.yjmcc.2019.02.006. Epub 2019 Feb 13. J Mol Cell Cardiol. 2019. PMID: 30771309 Free PMC article.

3

Valproic acid confers functional pluripotency to human amniotic fluid stem cells in a transgene-free approach.

Moschidou D, Mukherjee S, Blundell MP, Drews K, Jones GN, Abdulrazzak H, Nowakowska B, Phoolchund A, Lay K, Ramasamy TS, Cananzi M, Nettersheim D, Sullivan M, Frost J, Moore G, Vermeesch JR, Fisk NM, Thrasher AJ, Atala A, Adjaye J, Schorle H, De Coppi P, Guillot PV. Moschidou D, et al. Among authors: lay k. Mol Ther. 2012 Oct;20(10):1953-67. doi: 10.1038/mt.2012.117. Epub 2012 Jul 3. Mol Ther. 2012. PMID: 22760542 Free PMC article.

4

Upregulating CXCR4 in human fetal mesenchymal stem cells enhances engraftment and bone mechanics in a mouse model of osteogenesis imperfecta.

Jones GN, Moschidou D, Lay K, Abdulrazzak H, Vanleene M, Shefelbine SJ, Polak J, de Coppi P, Fisk NM, Guillot PV. Jones GN, et al. Among authors: lay k. Stem Cells Transl Med. 2012 Jan;1(1):70-8. doi: 10.5966/sctm.2011-0007. Epub 2011 Dec 7. Stem Cells Transl Med. 2012. PMID: 23197643 Free PMC article.

5

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.

Eom T, Zhang C, Wang H, Lay K, Fak J, Noebels JL, Darnell RB. Eom T, et al. Among authors: lay k. Elife. 2013 Jan 22;2:e00178. doi: 10.7554/eLife.00178. Elife. 2013. PMID: 23359859 Free PMC article.

6

Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel DES mutation identified by whole exome sequencing.

Tse HF, Ho JC, Choi SW, Lee YK, Butler AW, Ng KM, Siu CW, Simpson MA, Lai WH, Chan YC, Au KW, Zhang J, Lay KW, Esteban MA, Nicholls JM, Colman A, Sham PC. Tse HF, et al. Hum Mol Genet. 2013 Apr 1;22(7):1395-403. doi: 10.1093/hmg/dds556. Epub 2013 Jan 8. Hum Mol Genet. 2013. PMID: 23300193

7

Stem cells repurpose proliferation to contain a breach in their niche barrier.

Lay K, Yuan S, Gur-Cohen S, Miao Y, Han T, Naik S, Pasolli HA, Larsen SB, Fuchs E. Lay K, et al. Elife. 2018 Dec 6;7:e41661. doi: 10.7554/eLife.41661. Elife. 2018. PMID: 30520726 Free PMC article.

8

A comprehensive analysis of the effects of the deaminase AID on the transcriptome and methylome of activated B cells.

Fritz EL, Rosenberg BR, Lay K, Mihailović A, Tuschl T, Papavasiliou FN. Fritz EL, et al. Among authors: lay k. Nat Immunol. 2013 Jul;14(7):749-55. doi: 10.1038/ni.2616. Epub 2013 May 26. Nat Immunol. 2013. PMID: 23708250 Free PMC article.

9

FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential.

Lay K, Kume T, Fuchs E. Lay K, et al. Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):E1506-15. doi: 10.1073/pnas.1601569113. Epub 2016 Feb 24. Proc Natl Acad Sci U S A. 2016. PMID: 26912458 Free PMC article.

10

In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators.

Lien WH, Polak L, Lin M, Lay K, Zheng D, Fuchs E. Lien WH, et al. Among authors: lay k. Nat Cell Biol. 2014 Feb;16(2):179-90. doi: 10.1038/ncb2903. Epub 2014 Jan 26. Nat Cell Biol. 2014. PMID: 24463605 Free PMC article.

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