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Inhibition of LRRK2 kinase activity stimulates macroautophagy.
Manzoni C, Mamais A, Dihanich S, Abeti R, Soutar MPM, Plun-Favreau H, Giunti P, Tooze SA, Bandopadhyay R, Lewis PA. Manzoni C, et al. Among authors: dihanich s. Biochim Biophys Acta. 2013 Dec;1833(12):2900-2910. doi: 10.1016/j.bbamcr.2013.07.020. Epub 2013 Aug 1. Biochim Biophys Acta. 2013. PMID: 23916833 Free PMC article.
Pathogenic Parkinson's disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation.
Manzoni C, Mamais A, Dihanich S, McGoldrick P, Devine MJ, Zerle J, Kara E, Taanman JW, Healy DG, Marti-Masso JF, Schapira AH, Plun-Favreau H, Tooze S, Hardy J, Bandopadhyay R, Lewis PA. Manzoni C, et al. Among authors: dihanich s. Biochem Biophys Res Commun. 2013 Nov 29;441(4):862-6. doi: 10.1016/j.bbrc.2013.10.159. Epub 2013 Nov 6. Biochem Biophys Res Commun. 2013. PMID: 24211199 Free PMC article.
LRRK2: a problem lurking in vesicle trafficking?
Dihanich S, Manzoni C. Dihanich S, et al. J Neurosci. 2011 Jul 6;31(27):9787-8. doi: 10.1523/JNEUROSCI.1976-11.2011. J Neurosci. 2011. PMID: 21734269 Free PMC article. No abstract available.
15 results