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Lack of significant effects of the type 2 diabetes susceptibility loci JAZF1, CDC123/CAMK1D, NOTCH2, ADAMTS9, THADA, and TSPAN8/LGR5 on diabetes and quantitative metabolic traits.
Schleinitz D, Tönjes A, Böttcher Y, Dietrich K, Enigk B, Koriath M, Scholz GH, Blüher M, Zeggini E, McCarthy MI, Kovacs P, Stumvoll M. Schleinitz D, et al. Among authors: mccarthy mi. Horm Metab Res. 2010 Jan;42(1):14-22. doi: 10.1055/s-0029-1233480. Epub 2009 Aug 10. Horm Metab Res. 2010. PMID: 19670153
Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism.
Liew CF, Groves CJ, Wiltshire S, Zeggini E, Frayling TM, Owen KR, Walker M, Hitman GA, Levy JC, O'rahilly S, Hattersley AT, Johnston DG, McCarthy MI. Liew CF, et al. Among authors: mccarthy mi. Diabetologia. 2004 Dec;47(12):2168-75. doi: 10.1007/s00125-004-1575-4. Epub 2004 Dec 15. Diabetologia. 2004. PMID: 15662557
TCF7L2: the biggest story in diabetes genetics since HLA?
Zeggini E, McCarthy MI. Zeggini E, et al. Among authors: mccarthy mi. Diabetologia. 2007 Jan;50(1):1-4. doi: 10.1007/s00125-006-0507-x. Diabetologia. 2007. PMID: 17096114 Free PMC article. No abstract available.
An association analysis of the HLA gene region in latent autoimmune diabetes in adults.
Desai M, Zeggini E, Horton VA, Owen KR, Hattersley AT, Levy JC, Walker M, Gillespie KM, Bingley PJ, Hitman GA, Holman RR, McCarthy MI, Clark A. Desai M, et al. Among authors: mccarthy mi. Diabetologia. 2007 Jan;50(1):68-73. doi: 10.1007/s00125-006-0513-z. Epub 2006 Dec 2. Diabetologia. 2007. PMID: 17143607 Free PMC article.
Disparate genetic influences on polycystic ovary syndrome (PCOS) and type 2 diabetes revealed by a lack of association between common variants within the TCF7L2 gene and PCOS.
Barber TM, Bennett AJ, Groves CJ, Sovio U, Ruokonen A, Martikainen H, Pouta A, Hartikainen AL, Elliott P, Wass JA, Järvelin MR, Zeggini E, Franks S, McCarthy MI. Barber TM, et al. Among authors: mccarthy mi. Diabetologia. 2007 Nov;50(11):2318-22. doi: 10.1007/s00125-007-0804-z. Epub 2007 Sep 6. Diabetologia. 2007. PMID: 17805508
Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.
Rafiq S, Melzer D, Weedon MN, Lango H, Saxena R, Scott LJ; DIAGRAM Consortium; Palmer CN, Morris AD, McCarthy MI, Ferrucci L, Hattersley AT, Zeggini E, Frayling TM. Rafiq S, et al. Among authors: mccarthy mi. Diabetologia. 2008 Dec;51(12):2205-13. doi: 10.1007/s00125-008-1160-3. Epub 2008 Oct 14. Diabetologia. 2008. PMID: 18853133 Free PMC article.
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor.
Ban M, Goris A, Lorentzen AR, Baker A, Mihalova T, Ingram G, Booth DR, Heard RN, Stewart GJ, Bogaert E, Dubois B, Harbo HF, Celius EG, Spurkland A, Strange R, Hawkins C, Robertson NP, Dudbridge F, Wason J, De Jager PL, Hafler D, Rioux JD, Ivinson AJ, McCauley JL, Pericak-Vance M, Oksenberg JR, Hauser SL, Sexton D, Haines J, Sawcer S; Wellcome Trust Case-Control Consortium (WTCCC); Compston A. Ban M, et al. Eur J Hum Genet. 2009 Oct;17(10):1309-13. doi: 10.1038/ejhg.2009.41. Epub 2009 Mar 18. Eur J Hum Genet. 2009. PMID: 19293837 Free PMC article.
775 results