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Genetic variation in healthy oldest-old.
Halaschek-Wiener J, Amirabbasi-Beik M, Monfared N, Pieczyk M, Sailer C, Kollar A, Thomas R, Agalaridis G, Yamada S, Oliveira L, Collins JA, Meneilly G, Marra MA, Madden KM, Le ND, Connors JM, Brooks-Wilson AR. Halaschek-Wiener J, et al. Among authors: collins ja. PLoS One. 2009 Aug 14;4(8):e6641. doi: 10.1371/journal.pone.0006641. PLoS One. 2009. PMID: 19680556 Free PMC article.
The Super-Seniors Study: Phenotypic characterization of a healthy 85+ population.
Halaschek-Wiener J, Tindale LC, Collins JA, Leach S, McManus B, Madden K, Meneilly G, Le ND, Connors JM, Brooks-Wilson AR. Halaschek-Wiener J, et al. Among authors: collins ja. PLoS One. 2018 May 24;13(5):e0197578. doi: 10.1371/journal.pone.0197578. eCollection 2018. PLoS One. 2018. PMID: 29795606 Free PMC article.
Reduced telomere length variation in healthy oldest old.
Halaschek-Wiener J, Vulto I, Fornika D, Collins J, Connors JM, Le ND, Lansdorp PM, Brooks-Wilson A. Halaschek-Wiener J, et al. Mech Ageing Dev. 2008 Nov;129(11):638-41. doi: 10.1016/j.mad.2008.07.004. Epub 2008 Aug 14. Mech Ageing Dev. 2008. PMID: 18765247
Mutations in the ABC1 gene in familial HDL deficiency with defective cholesterol efflux.
Marcil M, Brooks-Wilson A, Clee SM, Roomp K, Zhang LH, Yu L, Collins JA, van Dam M, Molhuizen HO, Loubster O, Ouellette BF, Sensen CW, Fichter K, Mott S, Denis M, Boucher B, Pimstone S, Genest J Jr, Kastelein JJ, Hayden MR. Marcil M, et al. Among authors: collins ja. Lancet. 1999 Oct 16;354(9187):1341-6. doi: 10.1016/s0140-6736(99)07026-9. Lancet. 1999. PMID: 10533863
A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington disease.
Bečanović K, Nørremølle A, Neal SJ, Kay C, Collins JA, Arenillas D, Lilja T, Gaudenzi G, Manoharan S, Doty CN, Beck J, Lahiri N, Portales-Casamar E, Warby SC, Connolly C, De Souza RA; REGISTRY Investigators of the European Huntington's Disease Network; Tabrizi SJ, Hermanson O, Langbehn DR, Hayden MR, Wasserman WW, Leavitt BR. Bečanović K, et al. Among authors: collins ja. Nat Neurosci. 2015 Jun;18(6):807-16. doi: 10.1038/nn.4014. Epub 2015 May 4. Nat Neurosci. 2015. PMID: 25938884
A fully humanized transgenic mouse model of Huntington disease.
Southwell AL, Warby SC, Carroll JB, Doty CN, Skotte NH, Zhang W, Villanueva EB, Kovalik V, Xie Y, Pouladi MA, Collins JA, Yang XW, Franciosi S, Hayden MR. Southwell AL, et al. Among authors: collins ja. Hum Mol Genet. 2013 Jan 1;22(1):18-34. doi: 10.1093/hmg/dds397. Epub 2012 Sep 21. Hum Mol Genet. 2013. PMID: 23001568 Free PMC article.
Targeted next-generation sequencing to diagnose disorders of HDL cholesterol.
Sadananda SN, Foo JN, Toh MT, Cermakova L, Trigueros-Motos L, Chan T, Liany H, Collins JA, Gerami S, Singaraja RR, Hayden MR, Francis GA, Frohlich J, Khor CC, Brunham LR. Sadananda SN, et al. Among authors: collins ja. J Lipid Res. 2015 Oct;56(10):1993-2001. doi: 10.1194/jlr.P058891. Epub 2015 Aug 8. J Lipid Res. 2015. PMID: 26255038 Free PMC article.
387 results