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Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.
Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S. Bilican B, et al. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5803-8. doi: 10.1073/pnas.1202922109. Epub 2012 Mar 26. Proc Natl Acad Sci U S A. 2012. PMID: 22451909 Free PMC article.
Derivation of neural precursor cells from human ES cells at 3% O(2) is efficient, enhances survival and presents no barrier to regional specification and functional differentiation.
Stacpoole SR, Bilican B, Webber DJ, Luzhynskaya A, He XL, Compston A, Karadottir R, Franklin RJ, Chandran S. Stacpoole SR, et al. Among authors: bilican b. Cell Death Differ. 2011 Jun;18(6):1016-23. doi: 10.1038/cdd.2010.171. Epub 2011 Jan 28. Cell Death Differ. 2011. PMID: 21274009 Free PMC article.
Using human induced pluripotent stem cells to treat retinal disease.
Borooah S, Phillips MJ, Bilican B, Wright AF, Wilmut I, Chandran S, Gamm D, Dhillon B. Borooah S, et al. Among authors: bilican b. Prog Retin Eye Res. 2013 Nov;37:163-81. doi: 10.1016/j.preteyeres.2013.09.002. Epub 2013 Oct 6. Prog Retin Eye Res. 2013. PMID: 24104210 Free PMC article. Review.
31 results