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miR-661 downregulates both Mdm2 and Mdm4 to activate p53.
Hoffman Y, Bublik DR, Pilpel Y, Oren M. Hoffman Y, et al. Among authors: pilpel y. Cell Death Differ. 2014 Feb;21(2):302-9. doi: 10.1038/cdd.2013.146. Epub 2013 Oct 18. Cell Death Differ. 2014. PMID: 24141721 Free PMC article.
A dual program for translation regulation in cellular proliferation and differentiation.
Gingold H, Tehler D, Christoffersen NR, Nielsen MM, Asmar F, Kooistra SM, Christophersen NS, Christensen LL, Borre M, Sørensen KD, Andersen LD, Andersen CL, Hulleman E, Wurdinger T, Ralfkiær E, Helin K, Grønbæk K, Ørntoft T, Waszak SM, Dahan O, Pedersen JS, Lund AH, Pilpel Y. Gingold H, et al. Among authors: pilpel y. Cell. 2014 Sep 11;158(6):1281-1292. doi: 10.1016/j.cell.2014.08.011. Cell. 2014. PMID: 25215487 Free article.
p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation.
Brosh R, Shalgi R, Liran A, Landan G, Korotayev K, Nguyen GH, Enerly E, Johnsen H, Buganim Y, Solomon H, Goldstein I, Madar S, Goldfinger N, Børresen-Dale AL, Ginsberg D, Harris CC, Pilpel Y, Oren M, Rotter V. Brosh R, et al. Among authors: pilpel y. Mol Syst Biol. 2008;4:229. doi: 10.1038/msb.2008.65. Epub 2008 Nov 25. Mol Syst Biol. 2008. PMID: 19034270 Free PMC article.
117 results