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Functional whole-genome analysis identifies Polo-like kinase 2 and poliovirus receptor as essential for neuronal differentiation upstream of the negative regulator alphaB-crystallin.
Draghetti C, Salvat C, Zanoguera F, Curchod ML, Vignaud C, Peixoto H, Di Cara A, Fischer D, Dhanabal M, Andreas G, Abderrahim H, Rommel C, Camps M. Draghetti C, et al. Among authors: dhanabal m. J Biol Chem. 2009 Nov 13;284(46):32053-65. doi: 10.1074/jbc.M109.009324. Epub 2009 Aug 21. J Biol Chem. 2009. PMID: 19700763 Free PMC article.
Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases.
Caldwell RD, Qiu H, Askew BC, Bender AT, Brugger N, Camps M, Dhanabal M, Dutt V, Eichhorn T, Gardberg AS, Goutopoulos A, Grenningloh R, Head J, Healey B, Hodous BL, Huck BR, Johnson TL, Jones C, Jones RC, Mochalkin I, Morandi F, Nguyen N, Meyring M, Potnick JR, Santos DC, Schmidt R, Sherer B, Shutes A, Urbahns K, Follis AV, Wegener AA, Zimmerli SC, Liu-Bujalski L. Caldwell RD, et al. Among authors: dhanabal m. J Med Chem. 2019 Sep 12;62(17):7643-7655. doi: 10.1021/acs.jmedchem.9b00794. Epub 2019 Aug 15. J Med Chem. 2019. PMID: 31368705
SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors.
Karra S, Xiao Y, Chen X, Liu-Bujalski L, Huck B, Sutton A, Goutopoulos A, Askew B, Josephson K, Jiang X, Shutes A, Shankar V, Noonan T, Garcia-Berrios G, Dong R, Dhanabal M, Tian H, Wang Z, Clark A, Goodstal S. Karra S, et al. Among authors: dhanabal m. Bioorg Med Chem Lett. 2013 May 15;23(10):3081-7. doi: 10.1016/j.bmcl.2013.03.008. Epub 2013 Mar 13. Bioorg Med Chem Lett. 2013. PMID: 23570792
Synthesis and SAR development of quinoline analogs as novel P2X7 receptor antagonists.
Xiao Y, Karra S, Goutopoulos A, Morse NT, Zhang S, Dhanabal M, Tian H, Seenisamy J, Jayadevan J, Caldwell R, Potnick J, Bleich M, Chekler E, Sherer B, Sriraman V. Xiao Y, et al. Among authors: dhanabal m. Bioorg Med Chem Lett. 2019 Jul 1;29(13):1660-1664. doi: 10.1016/j.bmcl.2019.04.033. Epub 2019 Apr 24. Bioorg Med Chem Lett. 2019. PMID: 31031055
Anti-angiogenic therapy as a cancer treatment paradigm.
Dhanabal M, Jeffers M, Larochelle WJ. Dhanabal M, et al. Curr Med Chem Anticancer Agents. 2005 Mar;5(2):115-30. doi: 10.2174/1568011053174882. Curr Med Chem Anticancer Agents. 2005. PMID: 15777219 Review.
Angioarrestin: an antiangiogenic protein with tumor-inhibiting properties.
Dhanabal M, LaRochelle WJ, Jeffers M, Herrmann J, Rastelli L, McDonald WF, Chillakuru RA, Yang M, Boldog FL, Padigaru M, McQueeney KD, Wu F, Minskoff SA, Shimkets RA, Lichenstein HS. Dhanabal M, et al. Cancer Res. 2002 Jul 1;62(13):3834-41. Cancer Res. 2002. PMID: 12097297
Homodimerization controls the fibroblast growth factor 9 subfamily's receptor binding and heparan sulfate-dependent diffusion in the extracellular matrix.
Kalinina J, Byron SA, Makarenkova HP, Olsen SK, Eliseenkova AV, Larochelle WJ, Dhanabal M, Blais S, Ornitz DM, Day LA, Neubert TA, Pollock PM, Mohammadi M. Kalinina J, et al. Among authors: dhanabal m. Mol Cell Biol. 2009 Sep;29(17):4663-78. doi: 10.1128/MCB.01780-08. Epub 2009 Jun 29. Mol Cell Biol. 2009. PMID: 19564416 Free PMC article.
Insights into differential endostatin activity.
Maclachlan TK, Dhanabal M. Maclachlan TK, et al. Among authors: dhanabal m. Cancer Biol Ther. 2004 Nov;3(11):1167-8. doi: 10.4161/cbt.3.11.1300. Epub 2004 Nov 16. Cancer Biol Ther. 2004. PMID: 15640617 No abstract available.
30 results