van Lohuizen M - Search Results

1

BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A.

Puppe J, Drost R, Liu X, Joosse SA, Evers B, Cornelissen-Steijger P, Nederlof P, Yu Q, Jonkers J, van Lohuizen M, Pietersen AM. Puppe J, et al. Among authors: van lohuizen m. Breast Cancer Res. 2009;11(4):R63. doi: 10.1186/bcr2354. Epub 2009 Aug 26. Breast Cancer Res. 2009. PMID: 19709408 Free PMC article.

2

Mouse model systems to study multistep tumorigenesis.

Berns A, van der Lugt N, Alkema M, van Lohuizen M, Domen J, Acton D, Allen J, Laird PW, Jonkers J. Berns A, et al. Among authors: van der lugt n, van lohuizen m. Cold Spring Harb Symp Quant Biol. 1994;59:435-47. doi: 10.1101/sqb.1994.059.01.049. Cold Spring Harb Symp Quant Biol. 1994. PMID: 7587098 No abstract available.

3

The trithorax-group and polycomb-group chromatin modifiers: implications for disease.

van Lohuizen M. van Lohuizen M. Curr Opin Genet Dev. 1999 Jun;9(3):355-61. doi: 10.1016/s0959-437x(99)80053-7. Curr Opin Genet Dev. 1999. PMID: 10377289 Review.

4

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

Jacobs JJ, Keblusek P, Robanus-Maandag E, Kristel P, Lingbeek M, Nederlof PM, van Welsem T, van de Vijver MJ, Koh EY, Daley GQ, van Lohuizen M. Jacobs JJ, et al. Among authors: van welsem t, van de vijver mj, van lohuizen m. Nat Genet. 2000 Nov;26(3):291-9. doi: 10.1038/81583. Nat Genet. 2000. PMID: 11062467

5

Polycomb complexes and silencing mechanisms.

Lund AH, van Lohuizen M. Lund AH, et al. Among authors: van lohuizen m. Curr Opin Cell Biol. 2004 Jun;16(3):239-46. doi: 10.1016/j.ceb.2004.03.010. Curr Opin Cell Biol. 2004. PMID: 15145347 Review.

6

Stem cells and cancer; the polycomb connection.

Valk-Lingbeek ME, Bruggeman SW, van Lohuizen M. Valk-Lingbeek ME, et al. Among authors: van lohuizen m. Cell. 2004 Aug 20;118(4):409-18. doi: 10.1016/j.cell.2004.08.005. Cell. 2004. PMID: 15315754 Free article. Review.

7

Association of BMI1 with polycomb bodies is dynamic and requires PRC2/EZH2 and the maintenance DNA methyltransferase DNMT1.

Hernández-Muñoz I, Taghavi P, Kuijl C, Neefjes J, van Lohuizen M. Hernández-Muñoz I, et al. Among authors: van lohuizen m. Mol Cell Biol. 2005 Dec;25(24):11047-58. doi: 10.1128/MCB.25.24.11047-11058.2005. Mol Cell Biol. 2005. PMID: 16314526 Free PMC article.

8

Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster.

Tolhuis B, de Wit E, Muijrers I, Teunissen H, Talhout W, van Steensel B, van Lohuizen M. Tolhuis B, et al. Among authors: van steensel b, van lohuizen m. Nat Genet. 2006 Jun;38(6):694-9. doi: 10.1038/ng1792. Epub 2006 Apr 20. Nat Genet. 2006. PMID: 16628213

9

The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigens.

Steele JC, Torr EE, Noakes KL, Kalk E, Moss PA, Reynolds GM, Hubscher SG, van Lohuizen M, Adams DH, Young LS. Steele JC, et al. Among authors: van lohuizen m. Br J Cancer. 2006 Nov 6;95(9):1202-11. doi: 10.1038/sj.bjc.6603369. Epub 2006 Oct 3. Br J Cancer. 2006. PMID: 17024127 Free PMC article.

10

Polycomb silencers control cell fate, development and cancer.

Sparmann A, van Lohuizen M. Sparmann A, et al. Among authors: van lohuizen m. Nat Rev Cancer. 2006 Nov;6(11):846-56. doi: 10.1038/nrc1991. Nat Rev Cancer. 2006. PMID: 17060944 Review.

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