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Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children.
Hancock DB, Romieu I, Shi M, Sienra-Monge JJ, Wu H, Chiu GY, Li H, del Rio-Navarro BE, Willis-Owen SA, Weiss ST, Raby BA, Gao H, Eng C, Chapela R, Burchard EG, Tang H, Sullivan PF, London SJ. Hancock DB, et al. PLoS Genet. 2009 Aug;5(8):e1000623. doi: 10.1371/journal.pgen.1000623. Epub 2009 Aug 28. PLoS Genet. 2009. PMID: 19714205 Free PMC article.
Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.
Himes BE, Hunninghake GM, Baurley JW, Rafaels NM, Sleiman P, Strachan DP, Wilk JB, Willis-Owen SA, Klanderman B, Lasky-Su J, Lazarus R, Murphy AJ, Soto-Quiros ME, Avila L, Beaty T, Mathias RA, Ruczinski I, Barnes KC, Celedón JC, Cookson WO, Gauderman WJ, Gilliland FD, Hakonarson H, Lange C, Moffatt MF, O'Connor GT, Raby BA, Silverman EK, Weiss ST. Himes BE, et al. Am J Hum Genet. 2009 May;84(5):581-93. doi: 10.1016/j.ajhg.2009.04.006. Epub 2009 May 7. Am J Hum Genet. 2009. PMID: 19426955 Free PMC article.
PDE11A associations with asthma: results of a genome-wide association scan.
DeWan AT, Triche EW, Xu X, Hsu LI, Zhao C, Belanger K, Hellenbrand K, Willis-Owen SA, Moffatt M, Cookson WO, Himes BE, Weiss ST, Gauderman WJ, Baurley JW, Gilliland F, Wilk JB, O'Connor GT, Strachan DP, Hoh J, Bracken MB. DeWan AT, et al. J Allergy Clin Immunol. 2010 Oct;126(4):871-873.e9. doi: 10.1016/j.jaci.2010.06.051. J Allergy Clin Immunol. 2010. PMID: 20920776 Free PMC article. No abstract available.
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.
Weidinger S, Willis-Owen SA, Kamatani Y, Baurecht H, Morar N, Liang L, Edser P, Street T, Rodriguez E, O'Regan GM, Beattie P, Fölster-Holst R, Franke A, Novak N, Fahy CM, Winge MC, Kabesch M, Illig T, Heath S, Söderhäll C, Melén E, Pershagen G, Kere J, Bradley M, Lieden A, Nordenskjold M, Harper JI, McLean WH, Brown SJ, Cookson WO, Lathrop GM, Irvine AD, Moffatt MF. Weidinger S, et al. Hum Mol Genet. 2013 Dec 1;22(23):4841-56. doi: 10.1093/hmg/ddt317. Epub 2013 Jul 25. Hum Mol Genet. 2013. PMID: 23886662 Free PMC article.
An epigenome-wide association study of total serum immunoglobulin E concentration.
Liang L, Willis-Owen SAG, Laprise C, Wong KCC, Davies GA, Hudson TJ, Binia A, Hopkin JM, Yang IV, Grundberg E, Busche S, Hudson M, Rönnblom L, Pastinen TM, Schwartz DA, Lathrop GM, Moffatt MF, Cookson WOCM. Liang L, et al. Nature. 2015 Apr 30;520(7549):670-674. doi: 10.1038/nature14125. Epub 2015 Feb 18. Nature. 2015. PMID: 25707804 Free PMC article.
Variants of DENND1B associated with asthma in children.
Sleiman PM, Flory J, Imielinski M, Bradfield JP, Annaiah K, Willis-Owen SA, Wang K, Rafaels NM, Michel S, Bonnelykke K, Zhang H, Kim CE, Frackelton EC, Glessner JT, Hou C, Otieno FG, Santa E, Thomas K, Smith RM, Glaberson WR, Garris M, Chiavacci RM, Beaty TH, Ruczinski I, Orange JS, Allen J, Spergel JM, Grundmeier R, Mathias RA, Christie JD, von Mutius E, Cookson WO, Kabesch M, Moffatt MF, Grunstein MM, Barnes KC, Devoto M, Magnusson M, Li H, Grant SF, Bisgaard H, Hakonarson H. Sleiman PM, et al. N Engl J Med. 2010 Jan 7;362(1):36-44. doi: 10.1056/NEJMoa0901867. Epub 2009 Dec 23. N Engl J Med. 2010. PMID: 20032318 Free article.
The Genetics and Genomics of Asthma.
Willis-Owen SAG, Cookson WOC, Moffatt MF. Willis-Owen SAG, et al. Annu Rev Genomics Hum Genet. 2018 Aug 31;19:223-246. doi: 10.1146/annurev-genom-083117-021651. Annu Rev Genomics Hum Genet. 2018. PMID: 30169121
49 results