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The Snf1-related kinase, Hunk, is essential for mammary tumor metastasis.
Wertheim GB, Yang TW, Pan TC, Ramne A, Liu Z, Gardner HP, Dugan KD, Kristel P, Kreike B, van de Vijver MJ, Cardiff RD, Reynolds C, Chodosh LA. Wertheim GB, et al. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15855-60. doi: 10.1073/pnas.0906993106. Epub 2009 Aug 28. Proc Natl Acad Sci U S A. 2009. PMID: 19717424 Free PMC article.
The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells.
Gerhardt DM, Pajcini KV, D'altri T, Tu L, Jain R, Xu L, Chen MJ, Rentschler S, Shestova O, Wertheim GB, Tobias JW, Kluk M, Wood AW, Aster JC, Gimotty PA, Epstein JA, Speck N, Bigas A, Pear WS. Gerhardt DM, et al. Among authors: wertheim gb. Genes Dev. 2014 Mar 15;28(6):576-93. doi: 10.1101/gad.227496.113. Genes Dev. 2014. PMID: 24637115 Free PMC article.
Increased mTOR activation in idiopathic multicentric Castleman disease.
Arenas DJ, Floess K, Kobrin D, Pai RL, Srkalovic MB, Tamakloe MA, Rasheed R, Ziglar J, Khor J, Parente SAT, Pierson SK, Martinez D, Wertheim GB, Kambayashi T, Baur J, Teachey DT, Fajgenbaum DC. Arenas DJ, et al. Among authors: wertheim gb. Blood. 2020 May 7;135(19):1673-1684. doi: 10.1182/blood.2019002792. Blood. 2020. PMID: 32206779 Free PMC article.
MAFB enhances oncogenic Notch signaling in T cell acute lymphoblastic leukemia.
Pajcini KV, Xu L, Shao L, Petrovic J, Palasiewicz K, Ohtani Y, Bailis W, Lee C, Wertheim GB, Mani R, Muthusamy N, Li Y, Meijerink JPP, Blacklow SC, Faryabi RB, Cherry S, Pear WS. Pajcini KV, et al. Among authors: wertheim gb. Sci Signal. 2017 Nov 14;10(505):eaam6846. doi: 10.1126/scisignal.aam6846. Sci Signal. 2017. PMID: 29138297 Free PMC article.
81 results