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Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, Combarros O, Zelenika D, Bullido MJ, Tavernier B, Letenneur L, Bettens K, Berr C, Pasquier F, Fiévet N, Barberger-Gateau P, Engelborghs S, De Deyn P, Mateo I, Franck A, Helisalmi S, Porcellini E, Hanon O; European Alzheimer's Disease Initiative Investigators; de Pancorbo MM, Lendon C, Dufouil C, Jaillard C, Leveillard T, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossù P, Piccardi P, Annoni G, Seripa D, Galimberti D, Hannequin D, Licastro F, Soininen H, Ritchie K, Blanché H, Dartigues JF, Tzourio C, Gut I, Van Broeckhoven C, Alpérovitch A, Lathrop M, Amouyel P. Lambert JC, et al. Among authors: jaillard c. Nat Genet. 2009 Oct;41(10):1094-9. doi: 10.1038/ng.439. Epub 2009 Sep 6. Nat Genet. 2009. PMID: 19734903 Free article.
The thioredoxin-like protein rod-derived cone viability factor (RdCVFL) interacts with TAU and inhibits its phosphorylation in the retina.
Fridlich R, Delalande F, Jaillard C, Lu J, Poidevin L, Cronin T, Perrocheau L, Millet-Puel G, Niepon ML, Poch O, Holmgren A, Van Dorsselaer A, Sahel JA, Léveillard T. Fridlich R, et al. Among authors: jaillard c. Mol Cell Proteomics. 2009 Jun;8(6):1206-18. doi: 10.1074/mcp.M800406-MCP200. Epub 2009 Mar 11. Mol Cell Proteomics. 2009. PMID: 19279044 Free PMC article.
Nxnl2 splicing results in dual functions in neuronal cell survival and maintenance of cell integrity.
Jaillard C, Mouret A, Niepon ML, Clérin E, Yang Y, Lee-Rivera I, Aït-Ali N, Millet-Puel G, Cronin T, Sedmak T, Raffelsberger W, Kinzel B, Trembleau A, Poch O, Bennett J, Wolfrum U, Lledo PM, Sahel JA, Léveillard T. Jaillard C, et al. Hum Mol Genet. 2012 May 15;21(10):2298-311. doi: 10.1093/hmg/dds050. Epub 2012 Feb 15. Hum Mol Genet. 2012. PMID: 22343139 Free PMC article.
The metabolic signaling of the nucleoredoxin-like 2 gene supports brain function.
Jaillard C, Ouechtati F, Clérin E, Millet-Puel G, Corsi M, Aït-Ali N, Blond F, Chevy Q, Gales L, Farinelli M, Dalkara D, Sahel JA, Portais JC, Poncer JC, Léveillard T. Jaillard C, et al. Redox Biol. 2021 Nov 25;48:102198. doi: 10.1016/j.redox.2021.102198. Online ahead of print. Redox Biol. 2021. PMID: 34856436 Free PMC article.
The disruption of the rod-derived cone viability gene leads to photoreceptor dysfunction and susceptibility to oxidative stress.
Cronin T, Raffelsberger W, Lee-Rivera I, Jaillard C, Niepon ML, Kinzel B, Clérin E, Petrosian A, Picaud S, Poch O, Sahel JA, Léveillard T. Cronin T, et al. Among authors: jaillard c. Cell Death Differ. 2010 Jul;17(7):1199-210. doi: 10.1038/cdd.2010.2. Epub 2010 Feb 5. Cell Death Differ. 2010. PMID: 20139892 Free PMC article.
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