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The effect of mGlu8 deficiency in animal models of psychiatric diseases.
Fendt M, Bürki H, Imobersteg S, van der Putten H, McAllister K, Leslie JC, Shaw D, Hölscher C. Fendt M, et al. Among authors: van der putten h. Genes Brain Behav. 2010 Feb;9(1):33-44. doi: 10.1111/j.1601-183X.2009.00532.x. Epub 2009 Aug 8. Genes Brain Behav. 2010. PMID: 19740090 Free article.
Differential roles of mGlu(7) and mGlu(8) in amygdala-dependent behavior and physiology.
Fendt M, Imobersteg S, Peterlik D, Chaperon F, Mattes C, Wittmann C, Olpe HR, Mosbacher J, Vranesic I, van der Putten H, McAllister KH, Flor PJ, Gee CE. Fendt M, et al. Among authors: van der putten h. Neuropharmacology. 2013 Sep;72:215-23. doi: 10.1016/j.neuropharm.2013.04.052. Epub 2013 May 7. Neuropharmacology. 2013. PMID: 23664812
mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity.
Fendt M, Schmid S, Thakker DR, Jacobson LH, Yamamoto R, Mitsukawa K, Maier R, Natt F, Hüsken D, Kelly PH, McAllister KH, Hoyer D, van der Putten H, Cryan JF, Flor PJ. Fendt M, et al. Among authors: van der putten h. Mol Psychiatry. 2008 Oct;13(10):970-9. doi: 10.1038/sj.mp.4002073. Epub 2007 Aug 21. Mol Psychiatry. 2008. PMID: 17712315
Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behavior.
Gee CE, Peterlik D, Neuhäuser C, Bouhelal R, Kaupmann K, Laue G, Uschold-Schmidt N, Feuerbach D, Zimmermann K, Ofner S, Cryan JF, van der Putten H, Fendt M, Vranesic I, Glatthar R, Flor PJ. Gee CE, et al. Among authors: van der putten h. J Biol Chem. 2014 Apr 18;289(16):10975-10987. doi: 10.1074/jbc.M113.542654. Epub 2014 Mar 4. J Biol Chem. 2014. PMID: 24596089 Free PMC article.
A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo.
Mitsukawa K, Yamamoto R, Ofner S, Nozulak J, Pescott O, Lukic S, Stoehr N, Mombereau C, Kuhn R, McAllister KH, van der Putten H, Cryan JF, Flor PJ. Mitsukawa K, et al. Among authors: van der putten h. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18712-7. doi: 10.1073/pnas.0508063102. Epub 2005 Dec 9. Proc Natl Acad Sci U S A. 2005. PMID: 16339898 Free PMC article.
126 results