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Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression.
Jädersten M, Saft L, Pellagatti A, Göhring G, Wainscoat JS, Boultwood J, Porwit A, Schlegelberger B, Hellström-Lindberg E. Jädersten M, et al. Among authors: wainscoat js. Haematologica. 2009 Dec;94(12):1762-6. doi: 10.3324/haematol.2009.011528. Epub 2009 Oct 1. Haematologica. 2009. PMID: 19797731 Free PMC article.
Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients.
Pellagatti A, Jädersten M, Forsblom AM, Cattan H, Christensson B, Emanuelsson EK, Merup M, Nilsson L, Samuelsson J, Sander B, Wainscoat JS, Boultwood J, Hellström-Lindberg E. Pellagatti A, et al. Among authors: wainscoat js. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11406-11. doi: 10.1073/pnas.0610477104. Epub 2007 Jun 18. Proc Natl Acad Sci U S A. 2007. PMID: 17576924 Free PMC article.
Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes.
Pellagatti A, Hellström-Lindberg E, Giagounidis A, Perry J, Malcovati L, Della Porta MG, Jädersten M, Killick S, Fidler C, Cazzola M, Wainscoat JS, Boultwood J. Pellagatti A, et al. Among authors: wainscoat js. Br J Haematol. 2008 Jul;142(1):57-64. doi: 10.1111/j.1365-2141.2008.07178.x. Epub 2008 May 8. Br J Haematol. 2008. PMID: 18477045 Free PMC article.
Advances in the 5q- syndrome.
Boultwood J, Pellagatti A, McKenzie AN, Wainscoat JS. Boultwood J, et al. Among authors: wainscoat js. Blood. 2010 Dec 23;116(26):5803-11. doi: 10.1182/blood-2010-04-273771. Epub 2010 Aug 23. Blood. 2010. PMID: 20733155 Free article. Review.
5q- syndrome.
Boultwood J, Pellagatti A, Wainscoat JS. Boultwood J, et al. Among authors: wainscoat js. Curr Pharm Des. 2012;18(22):3180-3. doi: 10.2174/1381612811209023180. Curr Pharm Des. 2012. PMID: 22571696 Review.
Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes.
Fernandez-Mercado M, Burns A, Pellagatti A, Giagounidis A, Germing U, Agirre X, Prosper F, Aul C, Killick S, Wainscoat JS, Schuh A, Boultwood J. Fernandez-Mercado M, et al. Among authors: wainscoat js. Haematologica. 2013 Dec;98(12):1856-64. doi: 10.3324/haematol.2013.086686. Epub 2013 Jul 5. Haematologica. 2013. PMID: 23831921 Free PMC article.
Gene expression profiling in the myelodysplastic syndromes.
Pellagatti A, Fidler C, Wainscoat JS, Boultwood J. Pellagatti A, et al. Among authors: wainscoat js. Hematology. 2005 Aug;10(4):281-7. doi: 10.1080/10245330500065680. Hematology. 2005. PMID: 16085540 Review.
Gene expression profiling of CD34+ cells in patients with the 5q- syndrome.
Boultwood J, Pellagatti A, Cattan H, Lawrie CH, Giagounidis A, Malcovati L, Della Porta MG, Jädersten M, Killick S, Fidler C, Cazzola M, Hellström-Lindberg E, Wainscoat JS. Boultwood J, et al. Among authors: wainscoat js. Br J Haematol. 2007 Nov;139(4):578-89. doi: 10.1111/j.1365-2141.2007.06833.x. Epub 2007 Oct 3. Br J Haematol. 2007. PMID: 17916100 Free article.
Genome-wide analysis of copy number changes and loss of heterozygosity in myelodysplastic syndrome with del(5q) using high-density single nucleotide polymorphism arrays.
Wang L, Fidler C, Nadig N, Giagounidis A, Della Porta MG, Malcovati L, Killick S, Gattermann N, Aul C, Boultwood J, Wainscoat JS. Wang L, et al. Among authors: wainscoat js. Haematologica. 2008 Jul;93(7):994-1000. doi: 10.3324/haematol.12603. Epub 2008 May 27. Haematologica. 2008. PMID: 18508791 Free article.
231 results