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Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice.
Rodriguez-Cuenca S, Cochemé HM, Logan A, Abakumova I, Prime TA, Rose C, Vidal-Puig A, Smith AC, Rubinsztein DC, Fearnley IM, Jones BA, Pope S, Heales SJ, Lam BY, Neogi SG, McFarlane I, James AM, Smith RA, Murphy MP. Rodriguez-Cuenca S, et al. Among authors: cocheme hm. Free Radic Biol Med. 2010 Jan 1;48(1):161-72. doi: 10.1016/j.freeradbiomed.2009.10.039. Epub 2009 Oct 23. Free Radic Biol Med. 2010. PMID: 19854266
Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat.
Robb EL, Gawel JM, Aksentijević D, Cochemé HM, Stewart TS, Shchepinova MM, Qiang H, Prime TA, Bright TP, James AM, Shattock MJ, Senn HM, Hartley RC, Murphy MP. Robb EL, et al. Among authors: cocheme hm. Free Radic Biol Med. 2015 Dec;89:883-94. doi: 10.1016/j.freeradbiomed.2015.08.021. Epub 2015 Oct 8. Free Radic Biol Med. 2015. PMID: 26454075 Free article.
Mitochondrial targeting of quinones: therapeutic implications.
Cochemé HM, Kelso GF, James AM, Ross MF, Trnka J, Mahendiran T, Asin-Cayuela J, Blaikie FH, Manas AR, Porteous CM, Adlam VJ, Smith RA, Murphy MP. Cochemé HM, et al. Mitochondrion. 2007 Jun;7 Suppl:S94-102. doi: 10.1016/j.mito.2007.02.007. Epub 2007 Mar 16. Mitochondrion. 2007. PMID: 17449335 Review.
Mitochondria-targeted antioxidants in the treatment of disease.
Smith RA, Adlam VJ, Blaikie FH, Manas AR, Porteous CM, James AM, Ross MF, Logan A, Cochemé HM, Trnka J, Prime TA, Abakumova I, Jones BA, Filipovska A, Murphy MP. Smith RA, et al. Among authors: cocheme hm. Ann N Y Acad Sci. 2008 Dec;1147:105-11. doi: 10.1196/annals.1427.003. Ann N Y Acad Sci. 2008. PMID: 19076435 Review.
Can antioxidants be effective therapeutics?
Cochemé HM, Murphy MP. Cochemé HM, et al. Curr Opin Investig Drugs. 2010 Apr;11(4):426-31. Curr Opin Investig Drugs. 2010. PMID: 20336590
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix.
Cochemé HM, Quin C, McQuaker SJ, Cabreiro F, Logan A, Prime TA, Abakumova I, Patel JV, Fearnley IM, James AM, Porteous CM, Smith RA, Saeed S, Carré JE, Singer M, Gems D, Hartley RC, Partridge L, Murphy MP. Cochemé HM, et al. Cell Metab. 2011 Mar 2;13(3):340-50. doi: 10.1016/j.cmet.2011.02.003. Cell Metab. 2011. PMID: 21356523 Free PMC article.
40 results