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Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice.
Rodriguez-Cuenca S, Cochemé HM, Logan A, Abakumova I, Prime TA, Rose C, Vidal-Puig A, Smith AC, Rubinsztein DC, Fearnley IM, Jones BA, Pope S, Heales SJ, Lam BY, Neogi SG, McFarlane I, James AM, Smith RA, Murphy MP. Rodriguez-Cuenca S, et al. Among authors: rubinsztein dc. Free Radic Biol Med. 2010 Jan 1;48(1):161-72. doi: 10.1016/j.freeradbiomed.2009.10.039. Epub 2009 Oct 23. Free Radic Biol Med. 2010. PMID: 19854266
Huntington's disease: from pathology and genetics to potential therapies.
Imarisio S, Carmichael J, Korolchuk V, Chen CW, Saiki S, Rose C, Krishna G, Davies JE, Ttofi E, Underwood BR, Rubinsztein DC. Imarisio S, et al. Among authors: rubinsztein dc. Biochem J. 2008 Jun 1;412(2):191-209. doi: 10.1042/BJ20071619. Biochem J. 2008. PMID: 18466116 Review.
Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.
Underwood BR, Imarisio S, Fleming A, Rose C, Krishna G, Heard P, Quick M, Korolchuk VI, Renna M, Sarkar S, García-Arencibia M, O'Kane CJ, Murphy MP, Rubinsztein DC. Underwood BR, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2010 Sep 1;19(17):3413-29. doi: 10.1093/hmg/ddq253. Epub 2010 Jun 21. Hum Mol Genet. 2010. PMID: 20566712 Free PMC article.
Complex inhibitory effects of nitric oxide on autophagy.
Sarkar S, Korolchuk VI, Renna M, Imarisio S, Fleming A, Williams A, Garcia-Arencibia M, Rose C, Luo S, Underwood BR, Kroemer G, O'Kane CJ, Rubinsztein DC. Sarkar S, et al. Among authors: rubinsztein dc. Mol Cell. 2011 Jul 8;43(1):19-32. doi: 10.1016/j.molcel.2011.04.029. Mol Cell. 2011. PMID: 21726807 Free PMC article.
Molecular and phenotypic characterization of a mouse model of oculopharyngeal muscular dystrophy reveals severe muscular atrophy restricted to fast glycolytic fibres.
Trollet C, Anvar SY, Venema A, Hargreaves IP, Foster K, Vignaud A, Ferry A, Negroni E, Hourde C, Baraibar MA, 't Hoen PA, Davies JE, Rubinsztein DC, Heales SJ, Mouly V, van der Maarel SM, Butler-Browne G, Raz V, Dickson G. Trollet C, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2010 Jun 1;19(11):2191-207. doi: 10.1093/hmg/ddq098. Epub 2010 Mar 5. Hum Mol Genet. 2010. PMID: 20207626
α-Synuclein impairs macroautophagy: implications for Parkinson's disease.
Winslow AR, Chen CW, Corrochano S, Acevedo-Arozena A, Gordon DE, Peden AA, Lichtenberg M, Menzies FM, Ravikumar B, Imarisio S, Brown S, O'Kane CJ, Rubinsztein DC. Winslow AR, et al. Among authors: rubinsztein dc. J Cell Biol. 2010 Sep 20;190(6):1023-37. doi: 10.1083/jcb.201003122. J Cell Biol. 2010. PMID: 20855506 Free PMC article.
444 results