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A FRET sensor for non-invasive imaging of amyloid formation in vivo.
Kaminski Schierle GS, Bertoncini CW, Chan FTS, van der Goot AT, Schwedler S, Skepper J, Schlachter S, van Ham T, Esposito A, Kumita JR, Nollen EAA, Dobson CM, Kaminski CF. Kaminski Schierle GS, et al. Among authors: bertoncini cw. Chemphyschem. 2011 Feb 25;12(3):673-680. doi: 10.1002/cphc.201000996. Epub 2011 Feb 9. Chemphyschem. 2011. PMID: 21308945 Free PMC article.
Direct observation of the interconversion of normal and toxic forms of α-synuclein.
Cremades N, Cohen SI, Deas E, Abramov AY, Chen AY, Orte A, Sandal M, Clarke RW, Dunne P, Aprile FA, Bertoncini CW, Wood NW, Knowles TP, Dobson CM, Klenerman D. Cremades N, et al. Among authors: bertoncini cw. Cell. 2012 May 25;149(5):1048-59. doi: 10.1016/j.cell.2012.03.037. Cell. 2012. PMID: 22632969 Free PMC article.
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease.
Tóth G, Gardai SJ, Zago W, Bertoncini CW, Cremades N, Roy SL, Tambe MA, Rochet JC, Galvagnion C, Skibinski G, Finkbeiner S, Bova M, Regnstrom K, Chiou SS, Johnston J, Callaway K, Anderson JP, Jobling MF, Buell AK, Yednock TA, Knowles TP, Vendruscolo M, Christodoulou J, Dobson CM, Schenk D, McConlogue L. Tóth G, et al. Among authors: bertoncini cw. PLoS One. 2014 Feb 14;9(2):e87133. doi: 10.1371/journal.pone.0087133. eCollection 2014. PLoS One. 2014. PMID: 24551051 Free PMC article.
Direct observations of amyloid β self-assembly in live cells provide insights into differences in the kinetics of Aβ(1-40) and Aβ(1-42) aggregation.
Esbjörner EK, Chan F, Rees E, Erdelyi M, Luheshi LM, Bertoncini CW, Kaminski CF, Dobson CM, Kaminski Schierle GS. Esbjörner EK, et al. Among authors: bertoncini cw. Chem Biol. 2014 Jun 19;21(6):732-42. doi: 10.1016/j.chembiol.2014.03.014. Epub 2014 May 22. Chem Biol. 2014. PMID: 24856820 Free PMC article.
34 results