McGovern D - Search Results

1

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, Zhang H, Frackelton EC, Hou C, Flory JH, Otieno G, Chiavacci RM, Grundmeier R, Castro M, Latiano A, Dallapiccola B, Stempak J, Abrams DJ, Taylor K, McGovern D; Western Regional Alliance for Pediatric IBD; Silber G, Wrobel I, Quiros A; International IBD Genetics Consortium; Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmuda MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ; NIDDK IBD Genetics Consortium; Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E; Belgian-French IBD Consortium; Wellcome Trust Case Control Consortium; Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwillam R, Tremelling M, Delukas P, Mansfield J, Jewell D, Satsangi J, Ma… See abstract for full author list ➔ Imielinski M, et al. Among authors: mcgovern d. Nat Genet. 2009 Dec;41(12):1335-40. doi: 10.1038/ng.489. Epub 2009 Nov 15. Nat Genet. 2009. PMID: 19915574 Free PMC article.

2

Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors.

van Heel DA, Udalova IA, De Silva AP, McGovern DP, Kinouchi Y, Hull J, Lench NJ, Cardon LR, Carey AH, Jewell DP, Kwiatkowski D. van Heel DA, et al. Among authors: mcgovern dp. Hum Mol Genet. 2002 May 15;11(11):1281-9. doi: 10.1093/hmg/11.11.1281. Hum Mol Genet. 2002. PMID: 12019209

3

Fine mapping of the IBD1 locus did not identify Crohn disease-associated NOD2 variants: implications for complex disease genetics.

van Heel DA, McGovern DP, Cardon LR, Dechairo BM, Lench NJ, Carey AH, Jewell DP. van Heel DA, et al. Am J Med Genet. 2002 Aug 15;111(3):253-9. doi: 10.1002/ajmg.10588. Am J Med Genet. 2002. PMID: 12210321

4

Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease.

Negoro K, McGovern DP, Kinouchi Y, Takahashi S, Lench NJ, Shimosegawa T, Carey A, Cardon LR, Jewell DP, van Heel DA. Negoro K, et al. Among authors: mcgovern dp. Gut. 2003 Apr;52(4):541-6. doi: 10.1136/gut.52.4.541. Gut. 2003. PMID: 12631666 Free PMC article.

5

The IBD6 Crohn's disease locus demonstrates complex interactions with CARD15 and IBD5 disease-associated variants.

van Heel DA, Dechairo BM, Dawson G, McGovern DP, Negoro K, Carey AH, Cardon LR, Mackay I, Jewell DP, Lench NJ. van Heel DA, et al. Hum Mol Genet. 2003 Oct 15;12(20):2569-75. doi: 10.1093/hmg/ddg281. Epub 2003 Aug 19. Hum Mol Genet. 2003. PMID: 12928481

6

Further evidence of IBD5/CARD15 (NOD2) epistasis in the susceptibility to ulcerative colitis.

McGovern DP, Van Heel DA, Negoro K, Ahmad T, Jewell DP. McGovern DP, et al. Am J Hum Genet. 2003 Dec;73(6):1465-6. doi: 10.1086/379745. Am J Hum Genet. 2003. PMID: 14655097 Free PMC article. No abstract available.

7

A common CTLA4 haplotype associated with coeliac disease.

Hunt KA, McGovern DP, Kumar PJ, Ghosh S, Travis SP, Walters JR, Jewell DP, Playford RJ, van Heel DA. Hunt KA, et al. Eur J Hum Genet. 2005 Apr;13(4):440-4. doi: 10.1038/sj.ejhg.5201357. Eur J Hum Genet. 2005. PMID: 15657618

8

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease.

McGovern DP, Hysi P, Ahmad T, van Heel DA, Moffatt MF, Carey A, Cookson WO, Jewell DP. McGovern DP, et al. Hum Mol Genet. 2005 May 15;14(10):1245-50. doi: 10.1093/hmg/ddi135. Epub 2005 Mar 24. Hum Mol Genet. 2005. PMID: 15790594

9

Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease.

van Heel DA, Ghosh S, Butler M, Hunt KA, Lundberg AM, Ahmad T, McGovern DP, Onnie C, Negoro K, Goldthorpe S, Foxwell BM, Mathew CG, Forbes A, Jewell DP, Playford RJ. van Heel DA, et al. Lancet. 2005 May 21-27;365(9473):1794-6. doi: 10.1016/S0140-6736(05)66582-8. Lancet. 2005. PMID: 15910952

10

Risks and benefits of azathioprine therapy.

McGovern DP, Jewell DP. McGovern DP, et al. Gut. 2005 Aug;54(8):1055-9. doi: 10.1136/gut.2004.053231. Gut. 2005. PMID: 16009676 Free PMC article.

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