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BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy.
Cerchietti LC, Hatzi K, Caldas-Lopes E, Yang SN, Figueroa ME, Morin RD, Hirst M, Mendez L, Shaknovich R, Cole PA, Bhalla K, Gascoyne RD, Marra M, Chiosis G, Melnick A. Cerchietti LC, et al. Among authors: hatzi k. J Clin Invest. 2010 Dec 1;120(12):4569-82. doi: 10.1172/JCI42869. Epub 2010 Nov 1. J Clin Invest. 2010. PMID: 21041953 Free PMC article.
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia.
Hurtz C, Hatzi K, Cerchietti L, Braig M, Park E, Kim YM, Herzog S, Ramezani-Rad P, Jumaa H, Müller MC, Hofmann WK, Hochhaus A, Ye BH, Agarwal A, Druker BJ, Shah NP, Melnick AM, Müschen M. Hurtz C, et al. Among authors: hatzi k. J Exp Med. 2011 Oct 24;208(11):2163-74. doi: 10.1084/jem.20110304. Epub 2011 Sep 12. J Exp Med. 2011. PMID: 21911423 Free PMC article.
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90.
Moulick K, Ahn JH, Zong H, Rodina A, Cerchietti L, Gomes DaGama EM, Caldas-Lopes E, Beebe K, Perna F, Hatzi K, Vu LP, Zhao X, Zatorska D, Taldone T, Smith-Jones P, Alpaugh M, Gross SS, Pillarsetty N, Ku T, Lewis JS, Larson SM, Levine R, Erdjument-Bromage H, Guzman ML, Nimer SD, Melnick A, Neckers L, Chiosis G. Moulick K, et al. Among authors: hatzi k. Nat Chem Biol. 2011 Sep 25;7(11):818-26. doi: 10.1038/nchembio.670. Nat Chem Biol. 2011. PMID: 21946277 Free PMC article.
Mechanisms of epigenetic deregulation in lymphoid neoplasms.
Jiang Y, Hatzi K, Shaknovich R. Jiang Y, et al. Among authors: hatzi k. Blood. 2013 May 23;121(21):4271-9. doi: 10.1182/blood-2012-12-451799. Blood. 2013. PMID: 23704048 Free PMC article. Review. No abstract available.
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.
Hatzi K, Jiang Y, Huang C, Garrett-Bakelman F, Gearhart MD, Giannopoulou EG, Zumbo P, Kirouac K, Bhaskara S, Polo JM, Kormaksson M, MacKerell AD Jr, Xue F, Mason CE, Hiebert SW, Prive GG, Cerchietti L, Bardwell VJ, Elemento O, Melnick A. Hatzi K, et al. Cell Rep. 2013 Aug 15;4(3):578-88. doi: 10.1016/j.celrep.2013.06.016. Epub 2013 Aug 1. Cell Rep. 2013. PMID: 23911289 Free PMC article.
36 results