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A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas.
Cerchietti LC, Lopes EC, Yang SN, Hatzi K, Bunting KL, Tsikitas LA, Mallik A, Robles AI, Walling J, Varticovski L, Shaknovich R, Bhalla KN, Chiosis G, Melnick A. Cerchietti LC, et al. Among authors: tsikitas la. Nat Med. 2009 Dec;15(12):1369-76. doi: 10.1038/nm.2059. Epub 2009 Nov 22. Nat Med. 2009. PMID: 19966776 Free PMC article.
DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation.
Shaknovich R, Cerchietti L, Tsikitas L, Kormaksson M, De S, Figueroa ME, Ballon G, Yang SN, Weinhold N, Reimers M, Clozel T, Luttrop K, Ekstrom TJ, Frank J, Vasanthakumar A, Godley LA, Michor F, Elemento O, Melnick A. Shaknovich R, et al. Among authors: tsikitas l. Blood. 2011 Sep 29;118(13):3559-69. doi: 10.1182/blood-2011-06-357996. Epub 2011 Aug 9. Blood. 2011. PMID: 21828137 Free PMC article.
IL10 receptor is a novel therapeutic target in DLBCLs.
Béguelin W, Sawh S, Chambwe N, Chan FC, Jiang Y, Choo JW, Scott DW, Chalmers A, Geng H, Tsikitas L, Tam W, Bhagat G, Gascoyne RD, Shaknovich R. Béguelin W, et al. Leukemia. 2015 Aug;29(8):1684-94. doi: 10.1038/leu.2015.57. Epub 2015 Mar 3. Leukemia. 2015. PMID: 25733167
Author Correction: A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas.
Cerchietti LC, Lopes EC, Yang SN, Hatzi K, Bunting KL, Tsikitas LA, Mallik A, Robles AI, Walling J, Varticovski L, Shaknovich R, Bhalla KN, Chiosis G, Melnick A. Cerchietti LC, et al. Among authors: tsikitas la. Nat Med. 2024 May;30(5):1503. doi: 10.1038/s41591-024-02957-0. Nat Med. 2024. PMID: 38570701 No abstract available.
Imaging in Upper Tract Urothelial Carcinoma: A Review.
Tsikitas LA, Hopstone MD, Raman A, Duddalwar V. Tsikitas LA, et al. Cancers (Basel). 2023 Oct 18;15(20):5040. doi: 10.3390/cancers15205040. Cancers (Basel). 2023. PMID: 37894407 Free PMC article. Review.