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First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure.
Zwirner S, Abu Rmilah AA, Klotz S, Pfaffenroth B, Kloevekorn P, Moschopoulou AA, Schuette S, Haag M, Selig R, Li K, Zhou W, Nelson E, Poso A, Chen H, Amiot B, Jia Y, Minshew A, Michalak G, Cui W, Rist E, Longerich T, Jung B, Felgendreff P, Trompak O, Premsrirut PK, Gries K, Muerdter TE, Heinkele G, Wuestefeld T, Shapiro D, Weissbach M, Koenigsrainer A, Sipos B, Ab E, Zacarias MO, Theisgen S, Gruenheit N, Biskup S, Schwab M, Albrecht W, Laufer S, Nyberg S, Zender L. Zwirner S, et al. Among authors: albrecht w. Cell. 2024 Mar 28;187(7):1666-1684.e26. doi: 10.1016/j.cell.2024.02.023. Epub 2024 Mar 14. Cell. 2024. PMID: 38490194 Free PMC article. Clinical Trial.
Integrated data from intravital imaging and HPLC-MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats.
Hassan R, Gerdemann A, Cramer B, Hobloss Z, Myllys M, González D, Albrecht W, Veerkamp J, Friebel A, Hoehme S, Esselen M, Degen GH, Humpf HU, Hengstler JG, Ghallab A. Hassan R, et al. Among authors: albrecht w. Arch Toxicol. 2024 Apr;98(4):1081-1093. doi: 10.1007/s00204-024-03688-4. Epub 2024 Mar 4. Arch Toxicol. 2024. PMID: 38436695
Chiral Seeded Growth of Gold Nanorods Into Fourfold Twisted Nanoparticles with Plasmonic Optical Activity.
Ni B, Mychinko M, Gómez-Graña S, Morales-Vidal J, Obelleiro-Liz M, Heyvaert W, Vila-Liarte D, Zhuo X, Albrecht W, Zheng G, González-Rubio G, Taboada JM, Obelleiro F, López N, Pérez-Juste J, Pastoriza-Santos I, Cölfen H, Bals S, Liz-Marzán LM. Ni B, et al. Among authors: albrecht w. Adv Mater. 2024 Jan;36(4):e2312066. doi: 10.1002/adma.202312066. Epub 2023 Dec 31. Adv Mater. 2024. PMID: 38161223 No abstract available.
Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Mattsson J, Marschall HU, Hoehme S, Stirnimann G, Schwab M, Boor P, Amann K, Schmitz J, Bräsen JH, Rahnenführer J, Edlund K, Karpen SJ, Simbrunner B, Reiberger T, Mandorfer M, Trauner M, Dawson PA, Lindström E, Hengstler JG. Ghallab A, et al. Among authors: albrecht w. J Hepatol. 2024 Feb;80(2):268-281. doi: 10.1016/j.jhep.2023.10.035. Epub 2023 Nov 7. J Hepatol. 2024. PMID: 37939855 Free PMC article.
279 results