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The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema.
Lambrechts D, Buysschaert I, Zanen P, Coolen J, Lays N, Cuppens H, Groen HJ, Dewever W, van Klaveren RJ, Verschakelen J, Wijmenga C, Postma DS, Decramer M, Janssens W. Lambrechts D, et al. Am J Respir Crit Care Med. 2010 Mar 1;181(5):486-93. doi: 10.1164/rccm.200909-1364OC. Epub 2009 Dec 10. Am J Respir Crit Care Med. 2010. PMID: 20007924
Genetics, epigenetics and pharmaco-(epi)genomics in angiogenesis.
Buysschaert I, Schmidt T, Roncal C, Carmeliet P, Lambrechts D. Buysschaert I, et al. Among authors: lambrechts d. J Cell Mol Med. 2008 Dec;12(6B):2533-51. doi: 10.1111/j.1582-4934.2008.00515.x. J Cell Mol Med. 2008. PMID: 19210754 Free PMC article. Review.
A variant at chromosome 9p21 is associated with recurrent myocardial infarction and cardiac death after acute coronary syndrome: the GRACE Genetics Study.
Buysschaert I, Carruthers KF, Dunbar DR, Peuteman G, Rietzschel E, Belmans A, Hedley A, De Meyer T, Budaj A, Van de Werf F, Lambrechts D, Fox KA. Buysschaert I, et al. Among authors: lambrechts d. Eur Heart J. 2010 May;31(9):1132-41. doi: 10.1093/eurheartj/ehq053. Epub 2010 Mar 15. Eur Heart J. 2010. PMID: 20231156 Free PMC article.
Genomic copy number determines functional expression of {beta}-defensin 2 in airway epithelial cells and associates with chronic obstructive pulmonary disease.
Janssens W, Nuytten H, Dupont LJ, Van Eldere J, Vermeire S, Lambrechts D, Nackaerts K, Decramer M, Cassiman JJ, Cuppens H. Janssens W, et al. Among authors: lambrechts d. Am J Respir Crit Care Med. 2010 Jul 15;182(2):163-9. doi: 10.1164/rccm.200905-0767OC. Epub 2010 Apr 8. Am J Respir Crit Care Med. 2010. PMID: 20378733
The association of the 4q25 susceptibility variant for atrial fibrillation with stroke is limited to stroke of cardioembolic etiology.
Lemmens R, Buysschaert I, Geelen V, Fernandez-Cadenas I, Montaner J, Schmidt H, Schmidt R, Attia J, Maguire J, Levi C, Jood K, Blomstrand C, Jern C, Wnuk M, Slowik A, Lambrechts D, Thijs V; International Stroke Genetics Consortium. Lemmens R, et al. Among authors: lambrechts d. Stroke. 2010 Sep;41(9):1850-7. doi: 10.1161/STROKEAHA.110.587980. Epub 2010 Jul 29. Stroke. 2010. PMID: 20671249
Comprehensive fine mapping of chr12q12-14 and follow-up replication identify activin receptor 1B (ACVR1B) as a muscle strength gene.
Windelinckx A, De Mars G, Huygens W, Peeters MW, Vincent B, Wijmenga C, Lambrechts D, Delecluse C, Roth SM, Metter EJ, Ferrucci L, Aerssens J, Vlietinck R, Beunen GP, Thomis MA. Windelinckx A, et al. Among authors: lambrechts d. Eur J Hum Genet. 2011 Feb;19(2):208-15. doi: 10.1038/ejhg.2010.173. Epub 2010 Nov 10. Eur J Hum Genet. 2011. PMID: 21063444 Free PMC article.
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
Schunkert H, König IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, Preuss M, Stewart AF, Barbalic M, Gieger C, Absher D, Aherrahrou Z, Allayee H, Altshuler D, Anand SS, Andersen K, Anderson JL, Ardissino D, Ball SG, Balmforth AJ, Barnes TA, Becker DM, Becker LC, Berger K, Bis JC, Boekholdt SM, Boerwinkle E, Braund PS, Brown MJ, Burnett MS, Buysschaert I; Cardiogenics; Carlquist JF, Chen L, Cichon S, Codd V, Davies RW, Dedoussis G, Dehghan A, Demissie S, Devaney JM, Diemert P, Do R, Doering A, Eifert S, Mokhtari NE, Ellis SG, Elosua R, Engert JC, Epstein SE, de Faire U, Fischer M, Folsom AR, Freyer J, Gigante B, Girelli D, Gretarsdottir S, Gudnason V, Gulcher JR, Halperin E, Hammond N, Hazen SL, Hofman A, Horne BD, Illig T, Iribarren C, Jones GT, Jukema JW, Kaiser MA, Kaplan LM, Kastelein JJ, Khaw KT, Knowles JW, Kolovou G, Kong A, Laaksonen R, Lambrechts D, Leander K, Lettre G, Li M, Lieb W, Loley C, Lotery AJ, Mannucci PM, Maouche S, Martinelli N, McKeown PP, Meisinger C, Meitinger T, Melander O, Merlini PA, Mooser V, Morgan T, Mühleisen TW, Muhlestein JB, Münzel T, Musunuru K, Nahrstaedt J, Nelson CP, Nöthen MM, Olivieri O, Patel RS, Patterson CC, Peters A, Peyvandi F, Q… See abstract for full author list ➔ Schunkert H, et al. Among authors: lambrechts d. Nat Genet. 2011 Mar 6;43(4):333-8. doi: 10.1038/ng.784. Nat Genet. 2011. PMID: 21378990 Free PMC article.
Identification and prioritization of NUAK1 and PPP1CC as positional candidate loci for skeletal muscle strength phenotypes.
Windelinckx A, De Mars G, Huygens W, Peeters MW, Vincent B, Wijmenga C, Lambrechts D, Aerssens J, Vlietinck R, Beunen G, Thomis MA. Windelinckx A, et al. Among authors: lambrechts d. Physiol Genomics. 2011 Sep 8;43(17):981-92. doi: 10.1152/physiolgenomics.00200.2010. Epub 2011 Jul 12. Physiol Genomics. 2011. PMID: 21750233 Free PMC article.
605 results