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European lactase persistence genotype shows evidence of association with increase in body mass index.
Kettunen J, Silander K, Saarela O, Amin N, Müller M, Timpson N, Surakka I, Ripatti S, Laitinen J, Hartikainen AL, Pouta A, Lahermo P, Anttila V, Männistö S, Jula A, Virtamo J, Salomaa V, Lehtimäki T, Raitakari O, Gieger C, Wichmann EH, Van Duijn CM, Smith GD, McCarthy MI, Järvelin MR, Perola M, Peltonen L. Kettunen J, et al. Among authors: mccarthy mi. Hum Mol Genet. 2010 Mar 15;19(6):1129-36. doi: 10.1093/hmg/ddp561. Epub 2009 Dec 16. Hum Mol Genet. 2010. PMID: 20015952 Free PMC article.
Metabolic cardiovascular disease risk factors in women with self-reported symptoms of oligomenorrhea and/or hirsutism: Northern Finland Birth Cohort 1966 Study.
Taponen S, Martikainen H, Järvelin MR, Sovio U, Laitinen J, Pouta A, Hartikainen AL, McCarthy MI, Franks S, Paldanius M, Ruokonen A; Northern Finland Birth Cohort 1966 Study. Taponen S, et al. Among authors: mccarthy mi. J Clin Endocrinol Metab. 2004 May;89(5):2114-8. doi: 10.1210/jc.2003-031720. J Clin Endocrinol Metab. 2004. PMID: 15126528
Large-scale analysis of the relationship between CYP11A promoter variation, polycystic ovarian syndrome, and serum testosterone.
Gaasenbeek M, Powell BL, Sovio U, Haddad L, Gharani N, Bennett A, Groves CJ, Rush K, Goh MJ, Conway GS, Ruokonen A, Martikainen H, Pouta A, Taponen S, Hartikainen AL, Halford S, Järvelin MR, Franks S, McCarthy MI. Gaasenbeek M, et al. Among authors: mccarthy mi. J Clin Endocrinol Metab. 2004 May;89(5):2408-13. doi: 10.1210/jc.2003-031640. J Clin Endocrinol Metab. 2004. PMID: 15126571
Analysis of multiple data sets reveals no association between the insulin gene variable number tandem repeat element and polycystic ovary syndrome or related traits.
Powell BL, Haddad L, Bennett A, Gharani N, Sovio U, Groves CJ, Rush K, Goh MJ, Conway GS, Ruokonen A, Martikainen H, Pouta A, Taponen S, Hartikainen AL, Halford S, Zeggini E, Järvelin MR, Franks S, McCarthy MI. Powell BL, et al. Among authors: mccarthy mi. J Clin Endocrinol Metab. 2005 May;90(5):2988-93. doi: 10.1210/jc.2004-2485. Epub 2005 Feb 10. J Clin Endocrinol Metab. 2005. PMID: 15705917
Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.
Maeda S, Tsukada S, Kanazawa A, Sekine A, Tsunoda T, Koya D, Maegawa H, Kashiwagi A, Babazono T, Matsuda M, Tanaka Y, Fujioka T, Hirose H, Eguchi T, Ohno Y, Groves CJ, Hattersley AT, Hitman GA, Walker M, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Kamatani N, McCarthy MI, Nakamura Y. Maeda S, et al. Among authors: mccarthy mi. J Hum Genet. 2005;50(6):283-292. doi: 10.1007/s10038-005-0253-9. Epub 2005 Jun 7. J Hum Genet. 2005. PMID: 15940393
Relationship between E23K (an established type II diabetes-susceptibility variant within KCNJ11), polycystic ovary syndrome and androgen levels.
Barber TM, Bennett AJ, Gloyn AL, Groves CJ, Sovio U, Ruokonen A, Martikainen H, Pouta A, Taponen S, Weedon MN, Hartikainen AL, Wass JA, Järvelin MR, Zeggini E, Franks S, McCarthy MI. Barber TM, et al. Among authors: mccarthy mi. Eur J Hum Genet. 2007 Jun;15(6):679-84. doi: 10.1038/sj.ejhg.5201802. Epub 2007 Mar 7. Eur J Hum Genet. 2007. PMID: 17342155
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM, Perry JR, Elliott KS, Lango H, Rayner NW, Shields B, Harries LW, Barrett JC, Ellard S, Groves CJ, Knight B, Patch AM, Ness AR, Ebrahim S, Lawlor DA, Ring SM, Ben-Shlomo Y, Jarvelin MR, Sovio U, Bennett AJ, Melzer D, Ferrucci L, Loos RJ, Barroso I, Wareham NJ, Karpe F, Owen KR, Cardon LR, Walker M, Hitman GA, Palmer CN, Doney AS, Morris AD, Smith GD, Hattersley AT, McCarthy MI. Frayling TM, et al. Among authors: mccarthy mi. Science. 2007 May 11;316(5826):889-94. doi: 10.1126/science.1141634. Epub 2007 Apr 12. Science. 2007. PMID: 17434869 Free PMC article.
775 results