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Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.
Ramonet D, Daher JP, Lin BM, Stafa K, Kim J, Banerjee R, Westerlund M, Pletnikova O, Glauser L, Yang L, Liu Y, Swing DA, Beal MF, Troncoso JC, McCaffery JM, Jenkins NA, Copeland NG, Galter D, Thomas B, Lee MK, Dawson TM, Dawson VL, Moore DJ. Ramonet D, et al. Among authors: yang l. PLoS One. 2011 Apr 6;6(4):e18568. doi: 10.1371/journal.pone.0018568. PLoS One. 2011. PMID: 21494637 Free PMC article.
Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease.
Ahuja M, Ammal Kaidery N, Yang L, Calingasan N, Smirnova N, Gaisin A, Gaisina IN, Gazaryan I, Hushpulian DM, Kaddour-Djebbar I, Bollag WB, Morgan JC, Ratan RR, Starkov AA, Beal MF, Thomas B. Ahuja M, et al. Among authors: yang l. J Neurosci. 2016 Jun 8;36(23):6332-51. doi: 10.1523/JNEUROSCI.0426-16.2016. J Neurosci. 2016. PMID: 27277809 Free PMC article.
Conditional transgenic mice expressing C-terminally truncated human alpha-synuclein (alphaSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons.
Daher JP, Ying M, Banerjee R, McDonald RS, Hahn MD, Yang L, Flint Beal M, Thomas B, Dawson VL, Dawson TM, Moore DJ. Daher JP, et al. Among authors: yang l. Mol Neurodegener. 2009 Jul 24;4:34. doi: 10.1186/1750-1326-4-34. Mol Neurodegener. 2009. PMID: 19630976 Free PMC article.
Minocycline enhances MPTP toxicity to dopaminergic neurons.
Yang L, Sugama S, Chirichigno JW, Gregorio J, Lorenzl S, Shin DH, Browne SE, Shimizu Y, Joh TH, Beal MF, Albers DS. Yang L, et al. J Neurosci Res. 2003 Oct 15;74(2):278-85. doi: 10.1002/jnr.10709. J Neurosci Res. 2003. PMID: 14515357
Mitochondrial permeability transition pore component cyclophilin D distinguishes nigrostriatal dopaminergic death paradigms in the MPTP mouse model of Parkinson's disease.
Thomas B, Banerjee R, Starkova NN, Zhang SF, Calingasan NY, Yang L, Wille E, Lorenzo BJ, Ho DJ, Beal MF, Starkov A. Thomas B, et al. Among authors: yang l. Antioxid Redox Signal. 2012 May 1;16(9):855-68. doi: 10.1089/ars.2010.3849. Epub 2011 Jun 16. Antioxid Redox Signal. 2012. PMID: 21529244 Free PMC article.
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