McKinsey TA - Search Results

1

A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase.

Monovich L, Vega RB, Meredith E, Miranda K, Rao C, Capparelli M, Lemon DD, Phan D, Koch KA, Chapo JA, Hood DB, McKinsey TA. Monovich L, et al. Among authors: mckinsey ta. FEBS Lett. 2010 Feb 5;584(3):631-7. doi: 10.1016/j.febslet.2009.12.014. Epub 2009 Dec 14. FEBS Lett. 2010. PMID: 20018189 Free article.

2

The CRM1 nuclear export receptor controls pathological cardiac gene expression.

Harrison BC, Roberts CR, Hood DB, Sweeney M, Gould JM, Bush EW, McKinsey TA. Harrison BC, et al. Among authors: mckinsey ta. Mol Cell Biol. 2004 Dec;24(24):10636-49. doi: 10.1128/MCB.24.24.10636-10649.2004. Mol Cell Biol. 2004. PMID: 15572669 Free PMC article.

3

Protein kinase D directly phosphorylates histone deacetylase 5 via a random sequential kinetic mechanism.

Huynh QK, McKinsey TA. Huynh QK, et al. Among authors: mckinsey ta. Arch Biochem Biophys. 2006 Jun 15;450(2):141-8. doi: 10.1016/j.abb.2006.02.014. Epub 2006 Mar 9. Arch Biochem Biophys. 2006. PMID: 16584705

4

Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling.

Bush EW, Hood DB, Papst PJ, Chapo JA, Minobe W, Bristow MR, Olson EN, McKinsey TA. Bush EW, et al. Among authors: mckinsey ta. J Biol Chem. 2006 Nov 3;281(44):33487-96. doi: 10.1074/jbc.M605536200. Epub 2006 Sep 1. J Biol Chem. 2006. PMID: 16950785 Free article.

5

Protein kinase D1 stimulates MEF2 activity in skeletal muscle and enhances muscle performance.

Kim MS, Fielitz J, McAnally J, Shelton JM, Lemon DD, McKinsey TA, Richardson JA, Bassel-Duby R, Olson EN. Kim MS, et al. Among authors: mckinsey ta. Mol Cell Biol. 2008 Jun;28(11):3600-9. doi: 10.1128/MCB.00189-08. Epub 2008 Mar 31. Mol Cell Biol. 2008. PMID: 18378694 Free PMC article.

6

Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1.

Monovich L, Koch KA, Burgis R, Osimboni E, Mann T, Wall D, Gao J, Feng Y, Vega RB, Turner BA, Hood DB, Law A, Papst PJ, Koditek D, Chapo JA, Reid BG, Melvin LS, Pagratis NC, McKinsey TA. Monovich L, et al. Among authors: mckinsey ta. Biochim Biophys Acta. 2009 May;1789(5):422-31. doi: 10.1016/j.bbagrm.2009.04.001. Epub 2009 May 3. Biochim Biophys Acta. 2009. PMID: 19414071

7

Targeting histone deacetylases for heart failure.

Bush EW, McKinsey TA. Bush EW, et al. Among authors: mckinsey ta. Expert Opin Ther Targets. 2009 Jul;13(7):767-84. doi: 10.1517/14728220902939161. Expert Opin Ther Targets. 2009. PMID: 19466913 Review.

8

Protein acetylation in the cardiorenal axis: the promise of histone deacetylase inhibitors.

Bush EW, McKinsey TA. Bush EW, et al. Among authors: mckinsey ta. Circ Res. 2010 Feb 5;106(2):272-84. doi: 10.1161/CIRCRESAHA.109.209338. Circ Res. 2010. PMID: 20133912 Review.

9

Protein kinase C-related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases.

Harrison BC, Huynh K, Lundgaard GL, Helmke SM, Perryman MB, McKinsey TA. Harrison BC, et al. Among authors: mckinsey ta. FEBS Lett. 2010 Mar 19;584(6):1103-10. doi: 10.1016/j.febslet.2010.02.057. Epub 2010 Feb 24. FEBS Lett. 2010. PMID: 20188095 Free article.

10

Identification of orally available naphthyridine protein kinase D inhibitors.

Meredith EL, Ardayfio O, Beattie K, Dobler MR, Enyedy I, Gaul C, Hosagrahara V, Jewell C, Koch K, Lee W, Lehmann H, McKinsey TA, Miranda K, Pagratis N, Pancost M, Patnaik A, Phan D, Plato C, Qian M, Rajaraman V, Rao C, Rozhitskaya O, Ruppen T, Shi J, Siska SJ, Springer C, van Eis M, Vega RB, von Matt A, Yang L, Yoon T, Zhang JH, Zhu N, Monovich LG. Meredith EL, et al. Among authors: mckinsey ta. J Med Chem. 2010 Aug 12;53(15):5400-21. doi: 10.1021/jm100075z. J Med Chem. 2010. PMID: 20684591

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