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MMP12, lung function, and COPD in high-risk populations.
Hunninghake GM, Cho MH, Tesfaigzi Y, Soto-Quiros ME, Avila L, Lasky-Su J, Stidley C, Melén E, Söderhäll C, Hallberg J, Kull I, Kere J, Svartengren M, Pershagen G, Wickman M, Lange C, Demeo DL, Hersh CP, Klanderman BJ, Raby BA, Sparrow D, Shapiro SD, Silverman EK, Litonjua AA, Weiss ST, Celedón JC. Hunninghake GM, et al. Among authors: stidley c. N Engl J Med. 2009 Dec 31;361(27):2599-608. doi: 10.1056/NEJMoa0904006. Epub 2009 Dec 16. N Engl J Med. 2009. PMID: 20018959 Free PMC article. Clinical Trial.
Genotypes in matrix metalloproteinase 9 are a risk factor for COPD.
Tesfaigzi Y, Myers OB, Stidley CA, Schwalm K, Picchi M, Crowell RE, Gilliland FD, Belinsky SA. Tesfaigzi Y, et al. Int J Chron Obstruct Pulmon Dis. 2006;1(3):267-78. doi: 10.2147/copd.2006.1.3.267. Int J Chron Obstruct Pulmon Dis. 2006. PMID: 18046864 Free PMC article.
15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers.
Leng S, Liu Y, Weissfeld JL, Thomas CL, Han Y, Picchi MA, Edlund CK, Willink RP, Gaither Davis AL, Do KC, Nukui T, Zhang X, Burki EA, Van Den Berg D, Romkes M, Gauderman WJ, Crowell RE, Tesfaigzi Y, Stidley CA, Amos CI, Siegfried JM, Gilliland FD, Belinsky SA. Leng S, et al. Among authors: stidley ca. J Natl Cancer Inst. 2015 Feb 23;107(5):djv035. doi: 10.1093/jnci/djv035. J Natl Cancer Inst. 2015. PMID: 25713168 Free PMC article.
Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study.
Leng S, Stidley CA, Liu Y, Edlund CK, Willink RP, Han Y, Landi MT, Thun M, Picchi MA, Bruse SE, Crowell RE, Van Den Berg D, Caporaso NE, Amos CI, Siegfried JM, Tesfaigzi Y, Gilliland FD, Belinsky SA. Leng S, et al. Cancer Res. 2012 Feb 1;72(3):707-15. doi: 10.1158/0008-5472.CAN-11-3194. Epub 2011 Dec 2. Cancer Res. 2012. PMID: 22139380 Free PMC article.
Gene methylation biomarkers in sputum as a classifier for lung cancer risk.
Leng S, Wu G, Klinge DM, Thomas CL, Casas E, Picchi MA, Stidley CA, Lee SJ, Aisner S, Siegfried JM, Ramalingam S, Khuri FR, Karp DD, Belinsky SA. Leng S, et al. Among authors: stidley ca. Oncotarget. 2017 Jul 15;8(38):63978-63985. doi: 10.18632/oncotarget.19255. eCollection 2017 Sep 8. Oncotarget. 2017. PMID: 28969046 Free PMC article.
Defining a gene promoter methylation signature in sputum for lung cancer risk assessment.
Leng S, Do K, Yingling CM, Picchi MA, Wolf HJ, Kennedy TC, Feser WJ, Baron AE, Franklin WA, Brock MV, Herman JG, Baylin SB, Byers T, Stidley CA, Belinsky SA. Leng S, et al. Among authors: stidley ca. Clin Cancer Res. 2012 Jun 15;18(12):3387-95. doi: 10.1158/1078-0432.CCR-11-3049. Epub 2012 Apr 17. Clin Cancer Res. 2012. PMID: 22510351 Free PMC article.
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